1 Carcinomas 2 Heparam Sulfato 3 Plasma 4 Heparanases
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1. Identification and quantification of plasma heparanase isoforms in gastrointestinal carcinoma patients. / Identificação e quantificação das isoformas da heparanase em plasma de pacientes com carcinomas gatrointestinais.
Heparanase-1 (HPA1) is an endo-β-glucuronidase that degrades intradisaccharides glycosidic linkage between hexosamine and glucuronic acid into heparan sulfate chains, present on extracellular matrix and surface proteoglycans. HPA1 gene is located at 4q21.3 chromossome. Oligosaccharides generated by HPA1 are involved in cell proliferation, angiogenesis a
Publicado em: 2009