2 Deoxyribose
Mostrando 1-12 de 127 artigos, teses e dissertações.
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1. Antioxidant effects of crude extracts from Baccharis species: inhibition of myeloperoxidase activity, protection against lipid peroxidation, and action as oxidative species scavenger
The objective of this study was to show a comparison of the antioxidant properties of aqueous and ethanolic extracts obtained from Baccharis articulata (Lam.) Pers., Baccharis trimera (Less.) DC., Baccharis spicata (Lam.) Baill. and Baccharis usterii Heering, Asteraceae, by several techniques covering a range of oxidant species and of biotargets. We have inv
Revista Brasileira de Farmacognosia. Publicado em: 20/05/2011
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2. Avaliação da atividade antioxidante do ácido fítico de germe de milho
The obtained corn germ phytic acid (CGPA) antioxidant potential was evaluated through the deoxyribose, bathophenanthroline (BPS) and DPPH• assays. In the concentration of 130.5 μM of CGPA the hydroxyl radical maximum sequestering antioxidant activity was 29.3% while standard phytic acid (SPA) presented this maximum activity of 18.2% in the concentration o
Química Nova. Publicado em: 2009
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3. Estudo das propriedades antioxidantes de complexos nitrosilados de rutênio
This study shows the antioxidant and secondary the cytotoxic activity of five different ruthenium nitrosyl complexes: trans-[Ru(NH3)4(L)(NO)]Cl3 (A - D; being (A) L = Caffeine, (B) L = Theophylline, (C) L = Methyl-1-imidazole, (D) L = Benzoimidazole), and (E) cis-[Ru(NH3)4(NO)2]Cl3. Only the complex (A) (L = Caffeine) presented significant reactivity identif
Publicado em: 2009
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4. Mecanismos da ação antioxidante dos ácidos caféico e tânico em sistemas contendo íons ferro
Este trabalho foi dividido em três capítulos distintos. No primeiro capítulo, foi feita uma reavaliação da metodologia da degradação oxidativa da 2-desoxirribose (2-DR) em sistemas geradores de radicais livres mediados por íons ferrosos. Este ensaio é amplamente utilizado para avaliar a atividade pró/antioxidante de moléculas isoladas ou extratos
Publicado em: 2009
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5. Mecanismos de ação de antioxidantes de origem vegetal : estudo do polifenol ácido elágico e do extrato de caqui (Diospyros kaki)
The present work was divided in 2 chapters. In the first chapter, we investigated the antioxidant mechanism of ellagic acid (EA) to prevent oxyradical formation in a system containing Cu(II) plus ascorbate. The antioxidant property of persimmon pulp in oxidative processes mediated by Fe(III) in vitro was studied in the second chapter. EA study demonstrated t
Publicado em: 2008
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6. EFEITO DE INTERMEDIÁRIOS DO CICLO DE KREBS SOBRE ALTERAÇÕES OXIDATIVAS INDUZIDAS POR DIFERENTES AGENTES OXIDANTES / EFFECT OF KREBS CYCLE INTERMEDIATES ON OXIDATIVE CHANGES INDUCED BY DIFFERENT OXIDANT AGENTS
Recent data from the literature have suggested that some Krebs cycle intermediates could act as potent antioxidant agents, both in vitro and in vivo, against a variety of pro-oxidant agents. However, the mechanism(s) involved in the antioxidant effect of Krebs cycle intermediates are not fully understood. Additionally, there are scarce data in the literature
Publicado em: 2006
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7. Utilização da tecnica HPLC/APCI-MS/MS para determinação e identificação de danos ao DNA
Reactive oxygen species produce oxidized bases, deoxyribose lesions and DNA strand breaks in mammalian cells. Free radicaIs are produced in cells by cellular metabolism and by exogenous agents. These species react with biomolecules in cells, inc1udingDNA. The resulting damage to DNA, which is also called oxidative damage to DNA, is implicated in mutagenesis,
Publicado em: 2004
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8. 2-Deoxyribose Gene-Enzyme Complex in Salmonella typhimurium I. Isolation and Enzymatic Characterization of 2-Deoxyribose-Negative Mutants1
Salmonella typhimurium was found to utilize 2-deoxyribose as a sole carbon and energy source. Cells grown in the presence of deoxyribose contained increased levels of deoxyribose kinase, thymidine phosphorylase, and two forms of deoxyribose-5-phosphate aldolase (DR5P aldolase). One form of DR5P aldolase was induced by deoxyribose and coordinately regulated w
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9. 2-Deoxyribose Gene-Enzyme Complex in Salmonella typhimurium: Regulation of Phosphodeoxyribomutase
Phosphodeoxyribomutase, the enzyme which catalyzes the interconversion of 2-deoxyribose-1-phosphate to 2-deoxyribose-5-phosphate, has been partially purified from Salmonella typhimurium. The enzyme had an absolute requirement for manganese ion and was stimulated by glucose-1, 6-diphosphate. Phosphodeoxyribomutase was induced by deoxyribose-5-phosphate and wa
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10. Isolation and characterization of Selenomonas ruminantium strains capable of 2-deoxyribose utilization.
Microbes from ruminal contents of cattle were selectively enriched by using 2-deoxyribose (2DR) as a substrate for growth. Bacterial isolates growing on 2DR were gram-negative, curved, motile rods. The isolates grew on a broad range of substrates, including deoxyribose, glucose, ribose, mannitol, and lactate as well as ribonucleosides and deoxyribonucleoside
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11. The stereoselective enzymatic synthesis of 9-beta-D-2'-deoxyribofuranosyl 1-deazapurine.
The transfer of 2-deoxyribose from thymidine to 1-deazapurine which is catalysed by N-deoxyribosyl transferases from Lactobacillus leichmanii occurs in high yield. This is a very stereoselective process and only one product, 9-beta-D-2'-deoxyribofuranosyl 1-deazapurine, is formed. Nmr spectroscopy, and in particular, nuclear Overhauser enhancement experiment
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12. A comprehensive comparison of DNA replication past 2-deoxyribose and its tetrahydrofuran analog in Escherichia coli
Apurinic/apyrimidinic (AP) sites are alkali labile lesions that, when encountered during DNA replication, can block polymerases or potentially result in mutagenic events. Owing to the instability of 2-deoxyribose lesions (AP), a chemically stable tetrahydrofuran analog (F) is often used as a model of abasic sites. A comparison of the two lesions in Saccharom
Oxford University Press.