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Mostrando 1-12 de 305 artigos, teses e dissertações.
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1. Transfusion management for patients taking an anti-CD38 monoclonal antibody
Abstract Introduction: Pre-transfusion tests, essential for the release of blood components, may be affected by drugs. Monoclonal antibodies represent a class of medications increasingly used in the clinical practice, with anti-CD38 monoclonal antibodies (daratumumab) being a promising resource in the treatment of refractory myeloma. This monoclonal antibod
Hematol., Transfus. Cell Ther.. Publicado em: 2018-03
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2. Modelagem multinomial para a distribuição espacial do risco epidemiológico / Multinomial models to estimate the spatial risk in epidemiology
The search for understanding some epidemiological phenomena often involves an tool called spatial analysis of risk. The study of space in which certain outcomes occur allows the researcher to consider information that can not be collected through questionnaires or medical records. It also puts questions about what makes a certain area within the study region
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 21/06/2011
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3. Sintese de cimento osseo a base de a-TCP e estudo da influencia do Mg e do Si em suas propriedades finais / a-TCP calcium phosphate cement and the influence of Mg and Si substitution on its final properties
The need for new biomaterials which could improve life quality of people who suffer from oldness diseases or who have any bone tissue injury due to accidents and diseases like obesity and cancer are resulting in a growing number of researches. In this context, the development of new orthopedics biomaterials based on calcium phosphates compounds is relevant o
Publicado em: 2010
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4. Transição entre os comportamentos estendido e localizado em caminhadas estocásticas parcialmente auto-repulsivas em sistemas desordenados unidimensionais / Transition between the extended and localized regimes in stochastic partially self-avoiding walks in one-dimensional disordered systems
Consider $N$ sites randomly and uniformly distributed in a $d$-dimensional hypercube. A walker explores this disordered medium going to the nearest site, which has not been visited in the last $\mu$ (memory) steps. The walker trajectory is composed of a transient part and a periodic part (cycles). In this case, travelers can or cannot explore all available s
Publicado em: 2009
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5. The potential of DNA barcode in identifying neotropical birds species / O potencial do DNA barcode na identificação de espécies de aves neotropicais
The present study was organized in five chapters. The first one is a brief review of the literature on DNA barcode, pointing out its applications and limits. The results are presented in the three subsequent chapters. The second chapter aimed to evaluate the potential of the DNA barcoding method in the distinction of 783 samples of 228 different Neotropical
Publicado em: 2009
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6. Surface modification of synthetic clay aimed at biomolecule adsorption: synthesis and characterization
This work describes the process for functionalization of laponite through the grafting of 3-mercaptopropyltrimethoxysilane (MPTS). Laponite is synthetic smectite clay with surface area of 350 m²/g. The samples, prior to and after functionalization, were characterized by chemical analyses, thermogravimetric analysis (TGA), x ray diffraction (XRD), diffuse re
Materials Research. Publicado em: 2007-03
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7. Nanopartículas de Co suportadas em SiO2 : síntese, caracterização e propriedades catalíticas para a reforma a vapor do etanol.
Colloidal Co Nanoparticles (Co-NPs) were used to prepare supported Co catalysts. The Co- NPs were obtained by thermal decomposition of the precursor Co2(CO)8 in the presence of oleic acid and trioctylphosphine oxide (TOPO), in an inert atmosphere (Ar). The Co- NPs/SiO2 were obtained by impregnation of a colloidal suspension of nanoparticles on the support no
Publicado em: 2007
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8. Arquivos públicos brasileiros: a tranferência da informação na internet
A study about the various theoretical and technical aspects that characterize the process of transferring information published by the Brazilian public archival institutions on the internet. In order to fulfil such goal it was necessary to research the Brazilian public archival institutions on the internet, using the following criteria as guidelines: service
Publicado em: 2005
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9. mRNA accessible site tagging (MAST): a novel high throughput method for selecting effective antisense oligonucleotides
A solution-based method, mRNA accessible site tagging (MAST), has been developed to map the accessible sites of any given mRNA in high throughput fashion. mRNA molecules were immobilized and hybridized to randomized oligonucleotide libraries. Oligonucleotides specifically hybridized to the mRNA were sequenced and found to be able to precisely define the acce
Oxford University Press.
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10. Structural features of the 5' noncoding region of the rabbit globin messenger RNAs engaged in translation.
Accessible sites in the 5' noncoding region of the rabbit alpha- and beta-globin mRNAs were identified and compared in deproteinized RNA and in the mRNAs engaged in translation in the reticulocyte lysate. Preparations of RNA and lysate were subjected to limited nuclease digestion by RNase T1 and Neurospora endonuclease, and the cleavage sites were analyzed b
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11. Identifying ribozyme-accessible sites using NUH triplet-targeting gapmers
Accurately identifying accessible sites in RNA is a critical prerequisite for optimising the cleavage efficiency of hammerhead ribozymes and other small nucleozymes. Here we describe a simple RNase H-based procedure to rapidly identify hammerhead ribozyme-accessible sites in gene length RNAs. Twelve semi-randomised RNA–DNA–RNA chimeric oligonucleoti
Oxford University Press.
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12. Antigenic determinants in proteins coincide with surface regions accessible to large probes (antibody domains).
We evaluated surface areas on proteins that would be accessible to contacts with large (1-nm radius) spherical probes. Such spheres are comparable in size to antibody domains that contain antigen-combining sites. We found that all the reported antigenic sites correspond to segments particularly accessible to a large sphere. The antigenic sites were also evid