Actins
Mostrando 1-12 de 104 artigos, teses e dissertações.
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1. α-Smooth Muscle Actin and ACTA2 Gene Expressions in Vasculopathies
ABSTRACT α-smooth muscle actin, encoded by ACTA2 gene, is an isoform of the vascular smooth muscle actins, typically expressed in the vascular smooth muscle cells contributing to vascular motility and contraction. ACTA2 gene mutations cause a diversity of diffuse vasculopathies such as thoracic aortic aneurysms and dissections as well as occlusive vascular
Braz. J. Cardiovasc. Surg.. Publicado em: 2015-12
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2. Characterization of α-actin isoforms in white and red skeletal muscle types of Leporinus macrocephalus (Characiformes, Anostomidae)
ABSTRACT Two α-actin genes of the fish Leporinus macrocephalus, referring to white and red muscle tissues, were isolated. Actin isoforms, that mainly differed by a Ser/Ala155 substitution, can have a functional significance related to actin-ATP interaction. An Ala155 residue, as observed in the α-skeletal actin from red muscle, results in a decrease in act
An. Acad. Bras. Ciênc.. Publicado em: 27/11/2015
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3. O papel do jaspamídeo na dinâmica do citoesqueleto de actina das células de melanoma: relação com migração e invasão. / The role of jaspamide in the actin cytoskeleton of melanoma cells: the relation between migration and invasion.
No processo de metástase os movimentos de migração e invasão tem um papel essencial e em ambos a função dos microfilamentos é de grande importância. Neste contexto, o presente trabalho buscoui analisar os efeitos da droga jaspamídeo e após a determinação das concentrações de IC50 para as linhagens HT144 e NGM foram estudados os efeitos da droga
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 17/11/2011
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4. Will and knowledge as a basis for morality in Schopenhauer / Vontade e conhecimento como fundamento para a moral em Schopenhauer
This paper proposes to understand and reflect how the categories of will and knowledge are addressed in the philosophy of Schopenhauer and what relationship they have with the moral altruistic. For this we seek to understand the inversion that makes Schopenhauer in his philosophy on the intuitive and abstract and the delimitation of intellect and reason facu
Publicado em: 2010
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5. Identities among actin-encoding cDNAs of the Nile tilapia (Oreochromis niloticus) and other eukaryote species revealed by nucleotide and amino acid sequence analyses
Actin-encoding cDNAs of Nile tilapia (Oreochromis niloticus) were isolated by RT-PCR using total RNA samples of different tissues and further characterized by nucleotide sequencing and in silico amino acid (aa) sequence analysis. Comparisons among the actin gene sequences of O. niloticus and those of other species evidenced that the isolated genes present a
Genetics and Molecular Biology. Publicado em: 2008
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6. Identificação e caracterização de proteínas modificadas em enxertos de veias safenas humanas arterializadas no modelo ex vivo / Identification and characterization of modified proteins in arterialized human saphenous vein using an ex vivo system
A revascularização cardíaca utilizando a ponte de safena é um procedimento bastante utilizado para restabelecer o fluxo coronariano. Apesar do sucesso deste procedimento, a patência deste enxerto pode chegar a menos de 50% em 10 anos. Atribui-se parte deste insucesso a variações no processo adaptativo à nova condição hemodinâmica, onde o shear str
Publicado em: 2008
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7. Isolation and identification of actin-binding proteins in Plasmodium falciparum by affinity chromatography
The invasion of the erythrocyte by Plasmodium falciparum depends on the ability of the merozoite to move through the membrane invagination. This ability is probably mediated by actin dependent motors. Using affinity columns with G-actin and F-actin we isolated actin binding proteins from the parasite. By immunoblotting and immunoprecipitation with specific a
Memórias do Instituto Oswaldo Cruz. Publicado em: 2000-06
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8. Immunological differences between actins from cardiac muscle, skeletal muscle, and brain
The antigenic similarities and differences between various actins were explored by use of antisera against purified bovine cardiac actin and chicken embryo brain actin. In double-antibody coprecipitation tests, purified iodinated actins from bovine cardiac muscle, rabbit skeletal muscle, chicken embryo brain, and bovine brain all bound to antiserum against c
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9. Mammalian cytoplasmic actins are the products of at least two genes and differ in primary structure in at least 25 identified positions from skeletal muscle actins
Muscle and cytoplasmic actins from several species have been compared by extensive fingerprint analysis and by partial amino acid sequence determination with the known amino acid sequence of rabbit muscle actin. Although complete sequences have not been established, the following characteristics are apparent. (a) Cytoplasmic actins are the products of two di
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10. Actin Isoform-specific Conformational Differences Observed with Hydrogen/Deuterium Exchange and Mass Spectrometry*
Actin can exist in multiple conformations necessary for normal function. Actin isoforms, although highly conserved in sequence, exhibit different biochemical properties and cellular roles. We used amide proton hydrogen/deuterium (HD) exchange detected by mass spectrometry to analyze conformational differences between Saccharomyces cerevisiae and muscle actin
American Society for Biochemistry and Molecular Biology.
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11. Complete nucleotide sequence of a soybean actin gene
Soybean contains a small multigene family of actin-related sequences. We have determined the complete nucleotide sequence of a soybean actin gene carried on the recombinant plasmid pSAc3. As deduced from the nucleotide sequence, this soybean actin is composed of 376 amino acids. Compared to other eukaryotic actins, pSAc3 actin has a deletion of one amino aci
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12. Chick cytoplasmic actin and muscle actin have different structural genes.
Actins isolated from embryonic chick brain and muscle differ in mobility when subjected to electrophoresis in gels containing urea and sodium dodecyl sulfate. Experiments were carried out to determine whether these actins are products of different structural genes and differ in primary amino acid sequence, or whether they are products of the same structural