Acute And Chronic Schistosomiasis
Mostrando 1-12 de 20 artigos, teses e dissertações.
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1. Envolvimento cardíaco e pulmonar na esquistossomose aguda e crônica de camundongos alimentados com dieta hiperlipídica / Cardiac and pulmonary involvement on acute and chronic schistosomiasis in mice fed high-fat diet
O objetivo desse trabalho foi avaliar as alterações no tecido cardíaco e pulmonar de camundongos dislipidêmicos, esquistossomóticos e seus controles que haviam sido eutanasiados com 9 (fase aguda) e 17 (fase crônica) semanas de infecção. Foram estudados quatro grupos de camundongos, segundo a dieta e tempo de infecção: dieta padrão (SCa e SCc), di
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 14/03/2011
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2. The endemisation of schistosomiasis in Porto de Galinhas, Pernambuco, Brazil, 10 years after the first epidemic outbreak
In 2000, after heavy rains and floods in Porto de Galinhas, Pernambuco, Brazil, an outbreak of schistosomiasis was recorded, of which 62.2% (412 cases) were of the acute clinical form. Between 2001-2009, occasional findings of Biomphalaria snails parasitised by Schistosoma mansoni indicated that disease transmission was still occurring. This motivated a new
Memórias do Instituto Oswaldo Cruz. Publicado em: 2011-11
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3. Antibody reactivity against potato apyrase, a protein that shares epitopes with Schistosoma mansoni ATP diphosphohydrolase isoforms, in acute and chronically infected mice, after chemotherapy and reinfection
Schistosoma mansoni ATP diphosphohydrolase isoforms and potato apyrase share conserved epitopes. By enzyme-linked immunosorbent assays, elevated levels of IgM, IgG2a and IgG1 antibody reactivity against potato apyrase were observed in S. mansoni-infected BALB/c mice during the acute phase of infection, while only IgM and IgG1 antibody reactivity levels maint
Memórias do Instituto Oswaldo Cruz. Publicado em: 2010-07
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4. Cytokine profile associated with chronic and acute human schistosomiasis mansoni
The production and regulation of interleukin (IL) IL-13, IL-4 and interferon-gamma (IFN-³) was evaluated in 43 schistosomiasis patients with different clinical forms. Whole-blood cultures cytokine production in response to soluble egg antigen (SEA), soluble worm adult preparation (SWAP), mitogens, neutralizing antibodies or recombinant IL-13 were measured b
Memórias do Instituto Oswaldo Cruz. Publicado em: 2008-09
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5. Avaliação nutricional, anemia e helmintoses em área endêmica de Minas Gerais
The objective of this study was to evaluate the relationship between helminthiasis, nutritional status and anemia in a group of 212 children and adolescents from 2 to 17 years old living in an endemic area in the Jequitinhonha Valley, Minas Gerais. The prevalence of schistosomiasis was 75,9% and the geometric mean egg count per gram of feces (epg) was 128,82
Publicado em: 2007
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6. Desenvolvimento de um método sorológico para o diagnóstico laboratorial da esquistossomose mansoni baseado em peptídeos sintéticos / Development of a serologic method for laboratory diagnosis of the schistosomiasis mansoni based on synthetic peptides
Based on algorithms of hidrophilicity and flexibility, obtained by the use of the ProtScale software, disposable at the site http://au.expasy.org/cgi-bin/protscale.pl, seven potentially antigenic peptides were selected from different Schistosoma mansoni proteins: cathepsin B (Sm31), heat shock protein (SmHSP-70), cathodic circulating antigen (CCA) and the po
Publicado em: 2005
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7. Evaluation of tests based on the antibody response to keyhole limpet haemocyanin and soluble egg antigen to differentiate acute and chronic human schistosomiasis mansoni
Specific IgG and IgM responses to soluble egg antigen (SEA) and keyhole limpet haemocyanin (KLH) were measured by ELISA in patients with acute and chronic schistosomiasis. The tests based upon IgM and IgG antibodies responses to KLH presented the best diagnostic discrimination, and can be used in conjunction with clinical and epidemiological data to the diff
Memórias do Instituto Oswaldo Cruz. Publicado em: 2004-08
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8. Hypertensive portal colopathy in schistosomiasis mansoni: proposal for a classification
Portal hypertension is a frequent complication of chronic liver disease, detected not only in schistosomiasis, but also in cirrhosis of any etiology. Vascular alterations in the colonic mucosa are a potential source for acute or chronic bleeding and have been observed in patients with portal hypertension. The purpose of this prospective study was to describe
Memórias do Instituto Oswaldo Cruz. Publicado em: 2004-08
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9. Fibrose e outras lesÃes hepÃticas em camundongos isogÃnicos ("inbred") desnutridos e eutrÃficos, infectados com Schistosoma mansoni / Fibrosis and other hepatic lesions in undernourished and well-nourished inbred mice infected with
In chronic schistosomiasis mansoni, periovular granulomas and periportal fibrosis are the most important hepatic lesions, besides vascular changes that lead to hypertension within the portal venous system. Well-nourished Swiss outbred mice infected with Schistosoma mansoni develop lesions that mimick those found in advanced clinical forms of human intestinal
Publicado em: 2004
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10. Extramedullar proliferation of eosinophil granulocytes in chronic schistosomiasis mansoni is mediated by a factor secreted by inflammatory macrophages.
In chronic murine schistosomiasis mansoni, extramedullar myelopoiesis of eosinophils has been described, associated with tissue inflammatory infiltrates and periovular granulomas. It may be experimentally induced by intraperitoneal glass implants in mice with chronic schistosomiasis but not in normal mice or in mice with acute schistosomiasis. In vivo studie
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11. Alteration of granuloma angiotensin I-converting enzyme activity by regulatory T lymphocytes in murine schistosomiasis.
Granulomatous inflammatory lesions in murine schistosomiasis mansoni undergo a spontaneous diminution at the chronic phase of the disease concurrent with an increase in angiotensin I-converting enzyme (ACE) activity. The objective of this investigation was to determine whether T cells influence ACE activity within the granulomas. Cyclophosphamide and cimetid
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12. Utilization of fractionated soluble egg antigens reveals selectively modulated granulomatous and lymphokine responses during murine schistosomiasis mansoni.
Worm eggs deposited in the livers and intestines of Schistosoma mansoni-infected mice secrete soluble egg antigens (SEA) and induce T cell-mediated circumoval granulomas. In the present study, we fractionated crude SEA by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and tested the fractions for granuloma elicitation and lymphokine production at