Adipocyte Metabolism
Mostrando 1-12 de 62 artigos, teses e dissertações.
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1. Pros and cons of insulin administration on liver glucose metabolism in strength-trained healthy mice
Non-diabetic individuals use hormones like insulin to improve muscle strength and performance. However, as insulin also leads the liver and the adipose tissue to an anabolic state, the purpose of this study was to investigate the effects of insulin on liver metabolism in trained non-diabetic Swiss mice. The mice were divided into four groups: sedentary treat
Braz J Med Biol Res. Publicado em: 24/01/2019
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2. Renin-angiotensin system blockers regulate the metabolism of isolated fat cells in vitro
Due to the presence of the renin-angiotensin system (RAS) in tissues and its specific influence on white adipose tissue, fat cells are possible targets of pharmacological RAS blockers commonly used as anti-hypertensive drugs. In the present study, we investigated the effects of different RAS blockers on fat cell metabolism, more specifically on lipolysis, li
Braz J Med Biol Res. Publicado em: 28/07/2016
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3. Lipolysis and lipases in white adipose tissue – An update
Lipolysis is defined as the sequential hydrolysis of triacylglycerol (TAG) stored in cell lipid droplets. For many years, it was believed that hormone-sensitive lipase (HSL) and monoacylglycerol lipase (MGL) were the main enzymes catalyzing lipolysis in the white adipose tissue. Since the discovery of adipose triglyceride lipase (ATGL) in 2004, many studies
Arch. Endocrinol. Metab.. Publicado em: 2015-08
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4. Diverse coactivator recruitment through differential PPARγ nuclear receptor agonism
The PPARγ nuclear receptor regulates the expression of genes involved in lipid and carbohydrate metabolism, and it has protective effects in some patients with type 2 diabetes. Nevertheless, the therapeutic value of the PPARγ nuclear receptor protein is limited due to the secondary effects of some PPARγ ligands. Because the downstream effects of PPARγ ar
Genet. Mol. Biol.. Publicado em: 18/01/2013
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5. The effects of liposuction and exercise training on metabolic profile and body composition in adult normal weight healthy women / Efeitos da lipoaspiração acompanhada de treinamento físico no perfil metabólico e na composição corporal de mulheres adultas eutróficas e saudáveis
Liposuction is the most communly cosmetic surgery performed worlwide. Because adipose tissue is metabolicaly active, researchers have suggested that the surgical removal of fat through liposuction could benefically affect the metabolic profile. In addition, in many species, when body fat is removed, it is recovered rapidly due to compensatory fat growth at i
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 15/05/2011
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6. Agonistas PPAR (Rosiglitazona, Bezafibrato e Fenofibrato) e alterações bioquímicas e estruturais em órgãos-alvo de camundongos C57BL/6 alimentados com dieta hiperlipídica rica em sacarose / PPAR agonists (Rosiglitazone, Bezafibrate and Fenofibrate) and biochemical and structural changes in target organs of C57BL/6 mice fed a high-fat high-sucrose diet
This work aimed to evaluate the effect of peroxisome proliferator-activated receptor (PPAR) agonists (rosiglitazone, fenofibrate and bezafibrate) on lipid and glucose metabolism, body mass, and adipose and pancreatic tissue morphology in a model of diet-induced type 2 diabetes and overweight in mice. Two-month-old male C57BL/6 mice were fed a standard chow (
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 07/06/2010
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7. The adipocyte size contributes to the functional heterogeneity of white adipose tissue / O volume celular do adipócito contribui para a heterogeneidade funcional do tecido adiposo branco
The adipose tissue was considered to be a little active metabolic tissue, however, the most recent advances show that it plays an important function in the control of the energy homostasis. Based on this concept, this work aimed to characterize the morphology and metabolism of isolated adipocytes of three different depots, like: subcutaneous, periepididymal,
Publicado em: 2010
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8. Repercussões do destreinamento físico sobre o metabolismo e a celularidade do tecido adiposo branco periepididimal de ratos. / Physical detraining repercussions on metabolism and cellularity of white adipose tissue periepididymal in rats.
All adaptations acquired through physical training are reversible during inactivity. Significant reductions in maximal oxygen uptake (VO2Max) are observed within two-four weeks of detraining. Conversely, the consequences of detraining on adipose tissue are poorly known. The objective was to investigate the physical detraining effects on metabolism and cellul
Publicado em: 2010
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9. Effects of a PPARG gene variant on obesity characteristics in Brazil
The contribution of genetic factors to the development of obesity has been widely recognized, but the identity of the genes involved has not yet been fully clarified. Variation in genes involved in adipocyte differentiation and energy metabolism is expected to have a role in the etiology of obesity. We assessed the potential association of a polymorphism in
Publicado em: 2010
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10. Effects of a PPARG gene variant on obesity characteristics in Brazil
The contribution of genetic factors to the development of obesity has been widely recognized, but the identity of the genes involved has not yet been fully clarified. Variation in genes involved in adipocyte differentiation and energy metabolism is expected to have a role in the etiology of obesity. We assessed the potential association of a polymorphism in
Brazilian Journal of Medical and Biological Research. Publicado em: 04/05/2007
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11. Efeito do fenofibrato sobre o metabolismo de ratos com ou sem indução de esteatose hepática
The experiments reported here were designed to study the effect of fenofibrate (stimulant of peroxisome proliferator-activated receptor á - PPARá) and hepatic steatosis induced by orotic acid administration on the metabolism of adipose tissue and liver. Wistar male rats were divided into 4 experimental groups: 1) fed a balanced diet (C); 2) fed a balanced
Publicado em: 2007
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12. Heterogeneous response of adipose tissue to cancer cachexia
Cancer cachexia causes disruption of lipid metabolism. Since it has been well established that the various adipose tissue depots demonstrate different responses to stimuli, we assessed the effect of cachexia on some biochemical and morphological parameters of adipocytes obtained from the mesenteric (MES), retroperitoneal (RPAT), and epididymal (EAT) adipose
Brazilian Journal of Medical and Biological Research. Publicado em: 2001-09