Adrenergic Stimulus
Mostrando 1-12 de 45 artigos, teses e dissertações.
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1. Glycogen metabolism alterations of fed and fast diabetic rats salivary glands after secretagogues injection / Alterações do metabolismo de glicogênio das glândulas salivares de ratos diabéticos alimentados e em jejum após a injeção de sialogogos
O processo de secreção salivar é dependente de energia, consome glicose e pode mobilizar glicogênio na glândula submandibular. Nos ratos diabéticos a produção de saliva estimulada é reduzida e ocorre acúmulo de glicogênio nas glândulas parótida e submandibular. O objetivo deste trabalho foi avaliar in vivo o metabolismo de glicogênio das glând
Publicado em: 2008
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2. Inotropic effect of Citrus sinensis (L.) Osbeck leaf extracts on the guinea pig atrium
The objective of the present investigation was to determine the contractile effect of crude and acetone leaf extracts of Citrus sinensis (L.) Osb. on mammalian myocardium. Crude leaf extracts have been used in folk medicine to treat neurological disorders. Some flavonoids isolated from this plant presented a positive inotropic effect on myocardium. This moti
Brazilian Journal of Medical and Biological Research. Publicado em: 2005-01
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3. Catecholamine-induced vasoconstriction is sensitive to carbonic anhydrase I activation
We studied the relationship between alpha- and beta-adrenergic agonists and the activity of carbonic anhydrase I and II in erythrocyte, clinical and vessel studies. Kinetic studies were performed. Adrenergic agonists increased erythrocyte carbonic anhydrase as follows: adrenaline by 75%, noradrenaline by 68%, isoprenaline by 55%, and orciprenaline by 62%. Th
Brazilian Journal of Medical and Biological Research. Publicado em: 2001-03
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4. Substance P is a functional neurotransmitter in the rat parotid gland.
The technique of electrical field stimulation was employed to stimulate the intrinsic nerves of isolated rat parotid gland fragments. Responses to field stimulation were recorded as changes in enzyme secretion (amylase release), radiolabelled ion fluxes (86Rb efflux) and electrophysiological effects (changes in acinar cell membrane potential and input resist
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5. Discriminative Stimulus Effects of 1-(2,5-Dimethoxy-4-methylphenyl)-2-aminopropane (DOM), Ketanserin, and (R)-(+)-α-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-pipidinemethanol (MDL100907) in Rats
Very little is known about constitutive activity in vivo. This study examined whether constitutive activity and inverse agonism contribute to discriminative stimulus effects of drugs acting at serotonin (5-HT)2A receptors. Rats were trained to discriminate between saline and either 0.56 mg/kg 5-HT2 receptor agonist 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopro
The American Society for Pharmacology and Experimental Therapeutics.
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6. Noncoordinate regulation of cardiac Gs protein and beta-adrenergic receptors by a physiological stimulus, chronic dynamic exercise.
We used a physiological stimulus, chronic dynamic exercise, in pigs to examine resultant changes in chronotropic responsiveness to catecholamine and biochemical features of cardiac beta-adrenergic receptors and the stimulatory guanine nucleotide-binding protein, GS. Long-term treadmill running resulted in a substantial (44%) down-regulation of right atrial b
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7. Beta-adrenergic receptor mechanisms in rat parotid glands: activation by nerve stimulation and 3-isobutyl-1-methylxanthine.
The technique of electrical field stimulation (e.f.s.) was employed in conjunction with selective pharmacological antagonists to specifically investigate the role of endogenous neurotransmitter(s) in the activation of beta-adrenergic receptor mechanisms in isolated parotid gland segments of the rat. The field-stimulus-induced amylase release due to beta-adre
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8. Characteristics of the vagally driven non-adrenergic, non-cholinergic inhibitory innervation of ferret gastric corpus.
This paper reports a quantitative in vivo study on the vagal activation of the intramural non-adrenergic, non-cholinergic inhibitory nerves in the ferret gastric corpus. The nature of the inhibitory neurotransmitter was also investigated. In the atropinized, guanethidine-treated, urethane-anaesthetized ferret, electrical stimulation (10 s at 20 V, 1-20 Hz, 0
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9. An emotion-induced retrograde amnesia in humans is amygdala- and β-adrenergic-dependent
The influence of emotion on human memory is associated with two contradictory effects in the form of either emotion-induced enhancements or decrements in memory. In a series of experiments involving single word presentation, we show that enhanced memory for emotional words is strongly coupled to decrements in memory for items preceding the emotional stimulus
National Academy of Sciences.
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10. Regulation of a fos-lacZ fusion gene: a paradigm for quantitative analysis of stimulus-transcription coupling.
Expression of the c-fos protooncogene is induced by a great variety of extracellular stimuli. A fos-lacZ fusion gene has been constructed that recapitulates this regulation. The fos-lacZ gene was introduced into B104 neuroblastoma cells for use in a quantitative assay for stimulus-transcription coupling. Both alpha- and beta-adrenergic agonists, dibutyryl cA
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11. Is action potential duration of the intact dog heart related to contractility or stimulus rate?
1. The contractility (maximum rate of rise of left ventricular pressure) and action potential duration were measured in intact closed-chest anaesthetized dogs with complete atrioventricular dissociation and β-adrenergic blockade.
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12. Pharmacodynamic Studies of Beta Adrenergic Antagonism Induced in Man by Propranolol and Practolol
The pharmacodynamic activities of two beta adrenergic antagonists, propranolol and practolol, were compared in eight hypertensive patients. The activity of each antagonist was established in relation to its blood concentration at maximal and submaximal adrenergic blockade defined by inhibition of exercise tachycardia. Maximal inhibition of exercise tachycard