Adverse Drug Event
Mostrando 1-12 de 31 artigos, teses e dissertações.
-
1. Controversies in the treatment of postmenopausal osteoporosis: How long to treat with bisphosphonates?
ABSTRACT Osteoporosis is a systemic skeletal disease characterized by reduced bone mass and deterioration of bone tissue microarchitecture leading to an increased risk of fractures. Fragility fractures, especially hip fractures, are associated with a significant reduction in the physical function and quality of life of affected patients, as well as increased
Arch. Endocrinol. Metab.. Publicado em: 2020-08
-
2. Supporting people with severe mental health conditions during the COVID-19 pandemic: considerations for low- and middle-income countries using telehealth case management
ABSTRACT Osteoporosis is a systemic skeletal disease characterized by reduced bone mass and deterioration of bone tissue microarchitecture leading to an increased risk of fractures. Fragility fractures, especially hip fractures, are associated with a significant reduction in the physical function and quality of life of affected patients, as well as increased
Braz. J. Psychiatry. Publicado em: 2020-08
-
3. Treatment interruption of biological drugs and tofacitinib in rheumatoid arthritis: A systematic review of case reports
The aim of this study was to evaluate interruption of treatment with biological drugs and tofacitinib due to adverse events in patients with rheumatoid arthritis. A systematic review was performed in the electronic databases MEDLINE, Cochrane, Scopus, CRD, IPA, Lilacs and Scielo. Case reports addressing interruption of treatment due to any adverse event rela
Braz. J. Pharm. Sci.. Publicado em: 08/04/2019
-
4. Results From a 12-Month Open-Label Phase 1/2 Study of Velaglucerase Alfa in Children and Adolescents With Type 3 Gaucher Disease
Abstract Gaucher disease (GD) is an autosomal recessive lipid storage disorder, caused by deficient activity of the lysosomal enzyme b-glucocerebrosidase, resulting in accumulation of glucocerebroside in tissue macrophages. HGT-GCB-068 was an open-label study designed to explore the efficacy and safety of velaglucerase alfa in children and adolescents with t
J. inborn errors metab. screen.. Publicado em: 28/02/2019
-
5. Effectiveness of pharmacovigilance: multifaceted educational intervention related to the knowledge, skills and attitudes of multidisciplinary hospital staff
OBJECTIVES: Most educational interventions in pharmacovigilance are designed to encourage physicians to report adverse drug reactions. However, multidisciplinary teams may play an important role in reporting drug-related problems. This study assessed the impact of a multifaceted educational intervention in pharmacovigilance on the knowledge, skills and atti
Clinics. Publicado em: 2017-01
-
6. Antiviral treatment for Bell's palsy (idiopathic facial paralysis)
ABSTRACTBACKGROUND: Corticosteroids are widely used in the treatment of idiopathic facial paralysis (Bell's palsy), but the effectiveness of additional treatment with an antiviral agent is uncertain. Significant morbidity can be associated with severe cases of Bell's palsy.OBJECTIVES: To assess the effects of antiviral treatments alone or in combination with
Sao Paulo Med. J.. Publicado em: 2015-08
-
7. Influence of cyclosporine on the occurrence of nephrotoxicity after allogeneic hematopoietic stem cell transplantation: a systematic review
Cyclosporine, a drug used in immunosuppression protocols for hematopoietic stem cell transplantation that has a narrow therapeutic index, may cause various adverse reactions, including nephrotoxicity. This has a direct clinical impact on the patient. This study aims to summarize available evidence in the scientific literature on the use of cyclosporine in re
Rev. Bras. Hematol. Hemoter.. Publicado em: 2014-10
-
8. Acute pancreatitis associated with boceprevir: a case report
Approximately 170 million people are infected with hepatitis C, and the sustained virological response rate to treatment with pegylated interferon and ribavirin is 30–50%. In an attempt to improve the chances of cure, boceprevir is being added to therapy, but it is associated with an increased incidence of adverse events. We herein report a case of acute p
Braz J Infect Dis. Publicado em: 2014-08
-
9. Successful treatment of pulmonary Nocardia farcinica infection with linezolid: case report and literature review
Nocardia infection is rare but potentially fatal. Therapy of Nocardia infection remains difficult. Linezolid, a novel oxazolidinone antibiotic, has proven to be effective, but clinical data are limited. Here we describe a case of a 45-year-old man with pulmonary N. farcinica infection following a liver transplantation. The initial therapy was trimethoprim-su
Brazilian Journal of Infectious Diseases. Publicado em: 2011-10
-
10. Avaliação das interações medicamentosas potenciais para pacientes internados na clínica médica do Hospital Universitário da USP visando à elaboração de instrumento para identificação de eventos adversos a medicamentos evitáveis / Assessment of potential drug interactions for patients admitted to the internal medicine unit of the USP University Hospital in order to develop a measurement tool for identifying preventable adverse drug events
O estudo caracterizou o perfil biodemográfico e clínico dos pacientes internados na clínica médica do Hospital Universitário da USP e os fármacos prescritos, avaliou as prescrições médicas em relação à ocorrência ou não de interações medicamentosas potenciais (IMP) e os fatores relacionados a elas para elaboração de instrumento educativo pa
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 24/05/2010
-
11. Incidentes críticos relacionados aos eventos adversos a medicamentos em uma unidade de clínica médica de um hospital público do Estado do Amazonas / Critical incidents related to adverse drug events at a medical clinical unit in a public hospital of the state of Amazonas
Adverse drug events are common and will probably occur in any system, however, it is essential to identify their causes and try to minimize the risks to patientssafety. This descriptive study aimed to analyze adverse drug events at a public hospital in the state of Amazonas, based on the reports of the nursing team. The goal was to propose strategies for the
Publicado em: 2010
-
12. Frequency, types, and potential clinical significance of medication-dispensing errors
INTRODUCTION AND OBJECTIVES: Many dispensing errors occur in the hospital, and these can endanger patients. The purpose of this study was to assess the rate of dispensing errors by a unit dose drug dispensing system, to categorize the most frequent types of errors, and to evaluate their potential clinical significance. METHODS: A prospective study using a di
Clinics. Publicado em: 2009-01