African Derived Populations
Mostrando 1-12 de 24 artigos, teses e dissertações.
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1. Inherited hemoglobin disorders in an Afro-Amazonian community: Saracura
The most common hemoglobinopathies, viz, hemoglobins S and C, and α-and β-thalassemias, were investigated through the molecular screening of 116 subjects from the community of Saracura, comprising fugitive African slaves from farms of the municipality of Santarém, in the west of Pará State, Brazilian Amazon. The observed frequency of the HBB*S gene (0.9%
Genetics and Molecular Biology. Publicado em: 05/07/2012
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2. β-globin haplotypes in normal and hemoglobinopathic individuals from Reconcavo Baiano, State of Bahia, Brazil
Five restriction site polymorphisms in the β-globin gene cluster (HincII-5'ε, HindIII-Gγ, HindIII-ªγ, HincII-'ψβ1 and HincII-3''ψβ1) were analyzed in three populations (n = 114) from Reconcavo Baiano, State of Bahia, Brazil. The groups included two urban populations from the towns of Cachoeira and Maragojipe and one rural Afro-descendant population,
Genetics and Molecular Biology. Publicado em: 21/05/2010
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3. Ribeiro's typology, genomes, and Spanish colonialism, as viewed from Gran Canaria and Colombia
Four biallelic and six multiallelic Y-chromosome polymorphisms were investigated in 59 Gran Canarian, 60 North African Berber and 46 Spanish subjects. These new data were merged with equivalent literature information to obtain the parental Y-chrosomomal contribution in Gran Canarians, Colombians, and Venezuelans. The results were then compared, for Gran Cana
Publicado em: 2010
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4. Estudos de DNA mitocondrial em populações remanescentes de quilombos do Vale do Ribeira - São Paulo / Mitochondrial DNA investigations in African-derived quilombo populations of the Ribeira River Valley - São Paulo
O Vale do Ribeira é uma área que ocupa cerca de 10% da região sul do estado de São Paulo e abriga pelo menos 30 remanescentes de quilombos. Dessas, 24 já foram oficialmente reconhecidos ou estão em fase de reconhecimento. Com a finalidade de contribuir para o conhecimento da estrutura populacional e da história de formação dessas comunidades afro-de
Publicado em: 2009
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5. Genetic susceptibility and other risk factors associated to overweight and obesity in african-derived populations from the Ribeira River Valley - São Paulo / Susceptibilidade genética e outros fatores de risco associados ao sobrepeso e à obesidade em populações afro-descendentes do Vale do Ribeira-SP
Obesity, which is determined by multifactorial inheritance, is currently one of the most important issues concerning public health all over the world. Studies on the association of polymorphisms in genes with a possible role in the susceptibility to obesity have been conducted in different populations in the world, in order to elucidate the genetic basis tha
Publicado em: 2008
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6. Impacto da miscigenaÃÃo na aplicaÃÃo do HapMap para a populaÃÃo brasileira avaliados nos genes PTPN22 e VDR
The PTPN22 and VDR genes are commonly associated to several autoimmune diseases and complex phenotypes related to bone metabolism. The association of some of those polymorphisms are ethnic-specific, and therefore, admixture population studies must be conditionally evaluated to these factors. The Brazilian population is considered the most heterogeneous in th
Publicado em: 2007
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7. Prevalence of the A1555G (12S rRNA) and tRNA Ser(UCN) mitochondrial mutations in hearing-impaired Brazilian patients
Mitochondrial mutations are responsible for at least 1% of the cases of hereditary deafness, but the contribution of each mutation has not yet been defined in African-derived or native American genetic backgrounds. A total of 203 unselected hearing-impaired patients were screened for the presence of the mitochondrial mutation A1555G in the 12S rRNA gene and
Brazilian Journal of Medical and Biological Research. Publicado em: 2006-02
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8. Ribeiro's typology, genomes, and Spanish colonialism, as viewed from Gran Canaria and Colombia
Four biallelic and six multiallelic Y-chromosome polymorphisms were investigated in 59 Gran Canarian, 60 North African Berber and 46 Spanish subjects. These new data were merged with equivalent literature information to obtain the parental Y-chrosomomal contribution in Gran Canarians, Colombians, and Venezuelans. The results were then compared, for Gran Cana
Genetics and Molecular Biology. Publicado em: 2004
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9. Allele frequency distributions of six hypervariable loci (D1S80, APOB, D4S43, vW1, F13A and DYS19) in two African-Brazilian communities from the Amazon region
The allele frequency distributions of three VNTR (D1S80, APOB and D4S43) and three STR (vW1, F13A1 and DYS19) loci were investigated in two Afro-Brazilian populations from the Amazon: Curiau and Pacoval. Exact tests for population differentiation revealed significant differences in allele frequency between populations only for the D1S80 and APOB loci. A stat
Genetics and Molecular Biology. Publicado em: 2003
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10. Parental Analysis of Introgressive Hybridization between African and European Honeybees Using Nuclear DNA Rflps
African honeybees, introduced into Brazil 33 years ago, have spread through most of South and Central America and have largely replaced the extant European bees. Due to a paucity of genetic markers, genetic interactions between European and African bees are not well understood. Three restriction fragment length polymorphisms (RFLPs), detected with random, nu
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11. Linkage disequilibrium in human populations
Whereas the human linkage map appears on limited evidence to be constant over populations, maps of linkage disequilibrium (LD) vary among populations that differ in gene history. The greatest difference is between populations of sub-Saharan origin and populations remotely derived from Africa after a major bottleneck that reduced their heterozygosity and alte
The National Academy of Sciences.
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12. Putative Ancestral Origins of Chromosomal Segments in Individual African Americans: Implications for Admixture Mapping
Theoretically, markers that distinguish European from West African ancestry can be used to examine the origin of chromosomal segments in individual African Americans. In this study, putative ancestral origin was examined by using haplotypes estimated from genotyping 268 African Americans for 29 ancestry informative markers spaced over a 60-cM segment of chro
Cold Spring Harbor Laboratory Press.