Ah Nmr
Mostrando 1-12 de 13 artigos, teses e dissertações.
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1. Synthesis and in silico study of 2-furyl(4-{4-[(substituted)sulfonyl]benzyl}-1-piperazinyl)methanone derivatives as suitable therapeutic agents
Abstract In the study presented here, a new series of 2-furyl(4-{4-[(substituted)sulfonyl]benzyl}-1-piperazinyl)methanone derivatives was targeted. The synthesis was initiated by the treatment of different secondary amines (1a-h) with 4-bromomethylbenzenesulfonyl chloride (2) to obtain various 1-{[4-(bromomethyl)phenyl]sulfonyl}amines (3a-h). 2-Furyl(1-piper
Braz. J. Pharm. Sci.. Publicado em: 20/04/2017
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2. Plumeran alkaloids and glycosides from the seeds of aspidosperma pyrifolium mart.
A fração aquosa resultante da partição líquido-líquido do extrato etanólico de sementes de Aspidosperma pyrifolium apresentou atividades antinociceptiva e anti-inflamatória nos testes de formalina, contorção abdominal induzida pelo ácido acético e edema de pata por carragenina. O estudo fitoquímico conduziu ao isolamento de um novo alcaloide com
J. Braz. Chem. Soc.. Publicado em: 2014-11
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3. Características estruturais da matéria orgânica em Organossolos Háplicos. Seropédica: UFRRJ, 2010 / Structural characteristics of organic matter in Histosols. Seropédica: UFRRJ, 2010
Os Organossolos têm pequena representatividade geográfica no Brasil, entretanto, são utilizados intensamente em modelos de agricultura familiar e têm grande importância ambiental. Porém, a sua drenagem conduz ao processo de subsidência e outras modificações na matéria orgânica do solo (MOS), com implicações nas características dos Organossolos
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 27/08/2010
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4. Frações da matéria orgânica e composição molecular de substâncias húmicas de solos sob cultivo de eucalipto em biomas distintos / Organic matter fractions and humic substance molecular composition from soils under eucalypt cultivation in distinct biomes
O eucalipto é uma essência florestal de rápido crescimento que durante o ciclo e após a colheita aporta ao solo grande massa de resíduos, os quais podem contribuir para a formação da matéria orgânica do solo (MOS). A presente tese teve como objetivos gerais: i) avaliar o impacto do cultivo do eucalipto nas frações da MOS em solos de texturas disti
Publicado em: 2009
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5. ContribuiÃÃo ao conhecimento quÃmico de plantas do nordeste:Andira surinamensis e Piper divaricatum / Contribution to chemical knowledge of plants of northeast: Andira surinamensis e Piper divaricatum
This work describes the phytochemical investigation of extracts from the branch wood and branch barks of Andira surinamensis (Leguminosae), as well as, the volatile chemical composition of essential oil from leaves and fruits of Piper divaricatum G. Mey (Piperaceae). The phytochemical investigation of A. surinamensis extracts, using classic methods of chroma
Publicado em: 2007
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6. ContribuiÃÃo ao conhecimento quÃmico de plantas do nordeste do Brasil: Bauhinia ungulata L. (Leguminoseae) / Contribution of the chemical knowledge of plants of Northeast of Brazil
The Bauhinia genus possess 300 species distributed in tropical area of the planet. Species of this genus have been used in popular medicine on the diabetes treatment. Preliminary pharmacological studies showed hypoglicemic action of Bauhinia ungulata L. [1], popularly known on the northeast of Brazil as âpata-de-vacaâ, however, no phytochemical study has b
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 21/02/2006
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7. AplicaÃÃo da espectroscopia de ressonÃncia magnÃtica nuclear (RMN) Ã toxicologia forense
A RessonÃncia MagnÃtica Nuclear (RMN) e a Cromatografia em fase gasosa acoplada à espectrometria de massas (GC/MS) fornecem informaÃÃes sobre a estrutura quÃmica de substÃncias, bem como, sobre a constituiÃÃo qualitativa e quantitativa de amostras sem a necessidade de padrÃes de anÃlise ou prÃ-tratamento de amostras. Uma jovem estudante de 19 ano
Publicado em: 2006
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8. Novas pirimidinas: sÃntese e avaliaÃÃo de suas propiedades farmacolÃgicas
This work describes the synthesis of three series of compounds with pirimidinic ring and its pharmacological evaluations. First, the synthesis of compounds 4-amino-2,6-(diaryldissubistituted)- 5-carbonitrile-pyrimidines (5a-h) were achieved starting from arylamidine and bisnitriles. Second, the nitro-compounds (5k-o) have been reduced to their respective ami
Publicado em: 2003
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9. NMR and molecular modeling evidence for a G.A mismatch base pair in a purine-rich DNA duplex.
1H NMR experiments indicate that the oligomer 5'-d(ATGAGCGAATA) forms an unusual 10-base-pair duplex with 4 G.A base pairs (underlined) and a 3' unpaired adenosine. NMR results indicate that guanosine imino protons of the G.A mismatches are not hydrogen bonded but are stacked in the helix. A G----I substitution in either G.A base pair causes a dramatic decre
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10. NMR structure of a parallel-stranded DNA duplex at atomic resolution
DNA dodecamers have been designed with two cytosines on each end and intervening A and T stretches, such that the oligomers have fully complementary A:T base pairs when aligned in the parallel orientation. Spectroscopic (UV, CD and IR), NMR and molecular dynamics studies have shown that oligomers having the sequences d(CCATAATTTACC) and d(CCTATTAAATCC) form
Oxford University Press.
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11. Kinetics of the proton-deuteron exchange at position H8 of adenine and guanine in DNA.
Proton-NMR has been used to determine the activation energies and pre-exponential factors for the deuterium exchange of AH8 in poly(dA-dT).poly(dA-dT), and for GH8 in poly(dG-dC).poly(dG-dC). No simple relationship between the kinetic parameters and molecular conformation was found. By addition of 4.5 M NaCl a transition from the B to the Z conformation was
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12. Sequence specific molecular recognition by a monocationic lexitropsin of the decadeoxyribonucleotide d-[CATGGCCATG]2: structural and dynamic aspects deduced from high field 1H-NMR studies.
All 1H-NMR resonances of d-[CATGGCCATG]2 and the 1:1 complex of lexitropsin 1 and the DNA were assigned by the NOE difference, COSY and NOESY methods. Addition of 1 causes the base and imino protons for the sequence 5'-CCAT to undergo the most marked drug-induced chemical shift changes, thereby indicating that 1 is located in this base pair sequence. NOEs co