Allelic Dimorphism
Mostrando 1-7 de 7 artigos, teses e dissertações.
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1. Dimorfismo alélico na proteína de superfície MSP-6 de merozoítos de Plasmodium falciparum. / Allelic dimorphism in Plasmodium falciparum merozoite surface protein-6 (MSP-6).
The development of a vaccine against malaria caused by Plasmodium falciparum has been hampered by the high level of antigen polymorphism exhibited by this parasite. Allelic dimorphism is a pattern in which every observed allele of a gene is clearly grouped into one of two families. The dimorphic protein MSP-6 forms a complex with MSP-1 (also dimorphic) on me
Publicado em: 2008
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2. Caracterização molecular da deficiencia de proteina S
Human protein S is a plasmatic vitamin-K dependent glicoprotein that acts as a non-enzimatic cofactor of activated protein C in the protein C anticoagulant pathway. In addition to this protein S has an independent role that activated protein C, which is to inactivate factors Va and Xa. The plasmatic concentration of protein S is regulated by a C4b binding pr
Publicado em: 1998
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3. Allelic dimorphism of the erythocyte binding antigen-175 (eba-175) gene of Plasmodium falciparum and severe malaria: Significant association of the C-segment with fatal outcome in Ghanaian children
BioMed Central.
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4. HLA-C is the inhibitory ligand that determines dominant resistance to lysis by NK1- and NK2-specific natural killer cells.
Natural killer (NK) cells recognize alloantigens on normal cells. One of these alloantigens correlates with homozygosity for a dimorphism of HLA-C at positions 77-80, which is shared by a number of HLA-C alleles. A second allelic alloantigen correlates with homozygosity for the alternative HLA-C dimorphism, which is shared by the remaining HLA-C alleles. Mor
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5. Genetic dimorphism in influenza viruses: Characterization of stably associated hemagglutinin mutants differing in antigenicity and biological properties
Influenza virus recombinant X-53 produced for use in the 1976 National Immunization Program for swine influenza was found to comprise two types of virions differing in their antigenic, replicative, and plaque-forming characteristics. One type, characteristic of X-53 and designated “L,” was relatively low-yielding in chicken embryos, produced small clear
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6. The Mold-Specific MS8 Gene Is Required for Normal Hypha Formation in the Dimorphic Pathogenic Fungus Histoplasma capsulatum
The dimorphic fungus Histoplasma capsulatum is the etiologic agent of one of the most common systemic mycoses of humans, histoplasmosis. In the environment, H. capsulatum grows in a differentiated mold form and shifts to an undifferentiated yeast form after mold fragments or spores are inhaled. This mold-to-yeast shift is required for disease. Little is know
American Society for Microbiology.
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7. Hemagglutinin mutants of swine influenza virus differing in replication characteristics in their natural host.
In two mutant clones (L and H) of A/NJ/11/76 (Hsw 1N1) influenza viruses which differ slightly antigenically and markedly in replication characteristics in chicken embryos and Madin Darby canine kidney cells, these pleiotropic differences are mediated by mutation in the hemagglutinin gene (E. D. Kilbourne, Proc. Natl. Acad. Sci. U.S.A. 75:6258--6262, 1978).