Allodynia
Mostrando 1-12 de 53 artigos, teses e dissertações.
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1. Delay of neuropathic pain sensitization after application of dexamethasone-loaded implant in sciatic nerve-injured rats
Neuroimmune interactions underlying the development of pain sensitization in models of neuropathic pain have been widely studied. In this study, we evaluated the development of allodynia and its reduction associated with peripheral antineuroinflammatory effects induced by a dexamethasone-loaded biodegradable implant. Chronic constriction injury (CCI) of the
Braz. J. Pharm. Sci.. Publicado em: 20/12/2019
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2. THE ACTION OF SERICIN PROTEIN ON INITIAL NERVE REPAIR, ASSOCIATED OR NOT WITH SWIMMING IN WISTAR RATS
RESUMO Objetivo: Analisar os efeitos do tratamento da sericina, associada ou não ao exercício de natação com sobrecarga, sobre o reparo inicial do nervo isquiático após compressão em ratos Wistar. Métodos: Foram separados 40 animais em cinco grupos, sendo eles: controle; lesão; lesão-sericina; lesão-natação e lesão-sericina-natação. Durante
Coluna/Columna. Publicado em: 14/11/2019
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3. NF-kB mediated CX3CL1 activation in the dorsal root ganglion contributes to the maintenance of neuropathic pain induced in adult male Sprague Dawley rats
Abstract Purpose: To evaluate the role of CX3CL1 and NF-κB in the lumbar disc herniation induced neuropathic pain. Methods: After LDH induced by implantation of autologous nucleus pulposus (NP) on the left L5 nerve root was established, mechanical thresholds and thermal hyperalgesia were tested at relevant time points during an observation period of 28
Acta Cir. Bras.. Publicado em: 2018-07
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4. Interleukin-4 protects from chemotherapy-induced peripheral neuropathy in mice modal via the stimulation of IL-4/STAT6 signaling
Abstract Purpose: To investigate the possible role of IL-4 signaling pathway in vincristine-induced peripheral neuropathy. Methods: The mouse model of vincristine-induced peripheral neuropathy and interleukin (IL)-4 knockout mice were utilized to investigate the possible role of IL-4 signaling pathway in vincristine-induced peripheral neuropathy. Vincris
Acta Cir. Bras.. Publicado em: 2018-06
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5. A alodinia cutânea é mais frequente na migrânea crônica, mas sua presença e gravidade parecem estar associadas com a duração da doença
RESUMO Objetivo Avaliar a característica da alodinia cutânea em indivíduos com migrânea crônica e episódica em um hospital terciário. Métodos 80 sujeitos com migrânea episódica e 80 com migrânea crônica de um hospital terciário foram avaliados. O questionário 12-item Allodynia Symptom Checklist/Brasil foi aplicado e classificou os sujeitos
Arq. Neuro-Psiquiatr.. Publicado em: 2017-03
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6. Osteoarthritis model induced by intra-articular monosodium iodoacetate in rats knee
ABSTRACT PURPOSE: To evaluate the usefulness of a knee osteoarthritis model through functional, radiological and microscopic changes of the synovial membrane. METHODS: Forty eight rats were divided randomly into two groups. The first received 0.9% saline in the joint and corresponded to the control group. The second was submitted to experimental osteoarthr
Acta Cir. Bras.. Publicado em: 2016-11
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7. Lamina specific loss of inhibition may lead to distinct neuropathic manifestations: a computational modeling approach
Introduction It has been reported that inhibitory control at the superficial dorsal horn (SDH) can act in a regionally distinct manner, which suggests that regionally specific subpopulations of SDH inhibitory neurons may prevent one specific neuropathic condition. Methods In an attempt to address this issue, we provide an alternative approach by integrating
Res. Biomed. Eng.. Publicado em: 2015-04
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8. Quantitative methods for somatosensory evaluation in atypical odontalgia
A systematic review was conducted to identify reliable somatosensory evaluation methods for atypical odontalgia (AO) patients. The computerized search included the main databases (MEDLINE, EMBASE, and Cochrane Library). The studies included used the following quantitative sensory testing (QST) methods: mechanical detection threshold (MDT), mechanical pain th
Braz. oral res.. Publicado em: 23/01/2015
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9. Chronicity factors of temporomandibular disorders: a critical review of the literature
Facial pain often persists long after any identifiable organic pathology has healed. Moreover, in a subgroup of patients with temporomandibular disorder (TMD), no treatment is effective. Knowledge of factors associated with persistent pain in TMD could help identify personalized treatment approaches. Therefore, we conducted a critical review of the literatur
Braz. oral res.. Publicado em: 13/01/2015
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10. Expression of MMP-2 and MMP-9 in the rat trigeminal ganglion during the development of temporomandibular joint inflammation
Orofacial pain is a prevalent symptom in modern society. Some musculoskeletal orofacial pain is caused by temporomandibular disorders (TMDs). This condition has a multi-factorial etiology, including emotional factors and alteration of the masticator muscle and temporomandibular joints (TMJs). TMJ inflammation is considered to be a cause of pain in patients w
Braz J Med Biol Res. Publicado em: 18/11/2013
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11. Methadone in post-herpetic neuralgia: A pilot proof-of-concept study
OBJECTIVE: This research was designed as a pilot proof-of-concept study to evaluate the use of low-dose methadone in post-herpetic neuralgia patients who remained refractory after first and second line post-herpetic neuralgia treatments and had indications for adding an opioid agent to their current drug regimens. METHODS: This cross-over study was double b
Clinics. Publicado em: 2013-07
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12. ENVOLVIMENTO DE MASTÓCITOS EM UM MODELO DE DOR PÓS-OPERATÓRIA EM CAMUNDONGOS / INVOLVEMENT OF MAST CELLS IN A MODEL OF POSTOPERATIVE PAIN IN MICE
Estudos recentes indicam que praticamente a metade de todos os pacientes submetidos à procedimentos cirúrgicos apresentam um quadro de dor moderada à severa, o que torna importante entender os mecanismos envolvidos na dor pós-operatória para melhor tratá-la. Dados da literatura demonstram que incisões podem causar a degranulação de mastócitos. Assi
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 28/02/2012