Amebicidal
Mostrando 1-12 de 15 artigos, teses e dissertações.
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1. Terpenóides em espécies do gênero salvia (lamiaceae) / Terpenoids in the genus Salvia (Lamiaceae)
O gênero Salvia L. (Lamiaceae), constituido de aproximadamente 900 espécies, possui 60 representantes no Brasil. Dentre suas propriedades medicinais destacam-se as atividades antitumoral, anti-inflamatória, cicatrizante e antibacteriana. Óleos essenciais e diterpenos de núcleos abietano, clerodano, primarano estão entre os principais constituintes quí
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 2012
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2. Estudo químico e biológico de espécies de croton (euphorbiaceae) nativas do Rio Grande do Sul / Chemical and biological study of species of croton (Euphorbiaceae) native of Rio Grande do Sul
The family Euphorbiaceae has been highlighted by the production of compounds of industrial interest and importance for the food. Several representatives species are of interest due to production of volatile oils. Examples are species of Croton that have medicinal properties, such as anti-inflammatory, antifungal, antimicrobial and healing. Some species of th
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 2011
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3. Avaliação da atividade amebicida do óleo essencial de Pterocaulon polystachyum frente à Acantamoeba polyphaga / Amebicidal activy evaluation of pterocaulon polystachyum essencial oil against acanthamoeba polyphaga
Espécies de Acanthamoeba pertencem ao grupo das amebas de vida livre e constituem um agente etiológico da ceratite amebiana, doença que pode causar inflamação ocular grave e até mesmo cegueira. Plantas do gênero Pterocaulon (Asteraceae) são utilizadas na medicina popular como agente anti-séptico e antifúngico. Neste trabalho, foi investigada a comp
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 2011
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4. Atividade de pterocaulon polystachyum DC. (asteraceae) frente a acanthamoeba castellanii
O gênero Pterocaulon agrupa cerca de 20 espécies sendo 10 delas encontradas no Rio Grande do Sul. Várias espécies de Pterocaulon, conhecidas como "Quitoco", são utilizadas na medicina popular na forma de infusão ou decocto com diferentes fins terapêuticos. O extrato metanólico bruto e as frações de Pterocaulon polystachyum apresentam largo espectro
Publicado em: 2009
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5. Cytokine activation of murine macrophages for in vitro killing of Entamoeba histolytica trophozoites.
Macrophage-mediated effector mechanisms against the protozoan parasite Entamoeba histolytica were studied. Unstimulated macrophages were inefficient at killing E. histolytica trophozoites in vitro and were killed by the trophozoites. Conversely, immature cells of the mononuclear phagocyte lineage (promonocytes) were shown to display a strong spontaneous ameb
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6. Human T-lymphocyte proliferation, lymphokine production, and amebicidal activity elicited by the galactose-inhibitable adherence protein of Entamoeba histolytica.
We studied human T-lymphocyte responses to the purified Entamoeba histolytica galactose-inhibitable adherence protein. Individuals having serum anti-adherence protein antibodies possess peripheral blood lymphocytes which demonstrate antigen-specific responses to the purified adherence protein (10 micrograms/ml) and whole soluble amebic antigen (100 microgram
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7. Tumor necrosis factor alpha augments nitric oxide-dependent macrophage cytotoxicity against Entamoeba histolytica by enhanced expression of the nitric oxide synthase gene.
Nitric oxide (NO measured as nitrite, NO2-) is the major effector molecule produced by activated macrophages for in vitro cytotoxicity against Entamoeba histolytica trophozoites. In this study, we determine whether tumor necrosis factor alpha (TNF-alpha) produced by activated bone marrow-derived macrophages (BMM) is involved in the induction of the inducible
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8. Effects of magainins on ameba and cyst stages of Acanthamoeba polyphaga.
Amebic keratitis produced by Acanthamoeba spp. is an increasingly important ocular infection in extended-use contact lens wearers. Problems associated with the infection are compounded by the lack of effective and well-tolerated chemotherapeutic agents. The magainins, a group of naturally occurring and synthetic membrane-active peptide compounds, have been s
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9. The tumor necrosis factor alpha-stimulating region of galactose-inhibitable lectin of Entamoeba histolytica activates gamma interferon-primed macrophages for amebicidal activity mediated by nitric oxide.
Entamoeba histolytica adheres via galactose-lectin (Gal-lectin) to human colonic mucins and intestinal epithelial cells as a prerequisite to amebic invasion. Native Gal-lectin is a protective antigen in the gerbil model of amebiasis. Amino acids 596 to 1082 of Gal-lectin mediate E. histolytica adherence to target cells and stimulate tumor necrosis factor alp
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10. Inhibition of Acanthamoeba species by Pseudomonas aeruginosa: rationale for their selective exclusion in corneal ulcers and contact lens care systems.
Cocultivation of Acanthamoeba castellanii and Acanthamoeba polyphaga with live Pseudomonas aeruginosa and with broth filtrates of P. aeruginosa proved equally lethal to the Acanthamoeba spp. The P. aeruginosa-induced amebicidal activity is apparently toxin mediated and has two operative modes: it can function through binding of P. aeruginosa to the ameba mem
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11. Susceptibility of Acanthamoeba castellanii to contact lens disinfecting solutions.
A corneal isolate of Acanthamoeba castellanii was exposed to commercial contact lens disinfecting solutions containing hydrogen peroxide, benzalkonium chloride, polyaminopropyl biguanide, polyquaternium 1, and chlorhexidine-thimerosal. The minimum trophozoite amebicidal concentration and exposure times required to kill trophozoites and cysts were determined.
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12. Susceptibility testing of Dientamoeba fragilis ATCC 30948 with iodoquinol, paromomycin, tetracycline, and metronidazole.
Susceptibility testing was performed on Dientamoeba fragilis ATCC 30948 in a dixenic culture with Klebsiella pneumoniae and Bacteroides vulgatus. D. fragilis was cocultured with the bacteria in TYGM-9 medium (ATCC medium 1171). The activities of antiparasitic drugs were assessed by counting viable D. fragilis trophozoites with a hemacytometer by trypan blue