Amerindians Populations
Mostrando 1-12 de 37 artigos, teses e dissertações.
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1. Human leukocyte antigen allele linkage disequilibrium and haplotype structure in volunteer bone marrow donors of Paraná State
Abstract Background Bone marrow transplantation has been used in the treatment of various diseases, especially hematologic diseases. The success of this treatment, among other factors, requires human leukocyte antigens (HLA) compatibility between patient and donor. Knowing the human leukocyte antigens allele group and haplotype frequencies as well as the li
Rev. Bras. Hematol. Hemoter.. Publicado em: 2017-09
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2. Uniparental genetic markers in South Amerindians
A comprehensive review of uniparental systems in South Amerindians was undertaken. Variability in the Y-chromosome haplogroups were assessed in 68 populations and 1,814 individuals whereas that of Y-STR markers was assessed in 29 populations and 590 subjects. Variability in the mitochondrial DNA (mtDNA) haplogroup was examined in 108 populations and 6,697 pe
Genetics and Molecular Biology. Publicado em: 10/05/2012
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3. Genética de populações em genes de função imunológica: um estudo em populações Ameríndias / Population genetics of immune function genes: a study of Amerindian populations
Sinais de pressão seletiva têm sido descritos em vários genes. Dentre esses, os genes do sistema imune parecem ser um importante alvo de seleção natural. Diversos estudos têm demonstrado a atuação de pressões seletivas também modulando o padrão de diversidade de regiões reguladoras. Populações Ameríndias possuem uma história evolutiva relativ
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 02/08/2011
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4. Superoxide dismutase, catalase, glutathione peroxidase and gluthatione S-transferases M1 and T1 gene polymorphisms in three Brazilian population groups
Antioxidants such as superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPX1) reduce the oxidation rates in the organism. Gluthatione S-transferases (GSTs) play a vital role in phase 2 of biotransformation of many substances. Variation in the expression of these enzymes suggests individual differences for the degree of antioxidant protect
Genetics and Molecular Biology. Publicado em: 26/11/2010
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5. Analysis of paternal lineages in Brazilian and African populations
The present-day Brazilian population is a consequence of the admixture of various peoples of very different origins, namely, Amerindians, Europeans and Africans. The proportion of each genetic contribution is known to be very heterogeneous throughout the country. The aim of the present study was to compare the male lineages present in two distinct Brazilian
Genetics and Molecular Biology. Publicado em: 09/07/2010
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6. Mitochondrial DNA mapping of social-biological interactions in Brazilian Amazonian African-descendant populations
The formation of the Brazilian Amazonian population has historically involved three main ethnic groups, Amerindian, African and European. This has resulted in genetic investigations having been carried out using classical polymorphisms and molecular markers. To better understand the genetic variability and the micro-evolutionary processes acting in human gro
Publicado em: 2010
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7. DNA tests probe the genomic ancestry of Brazilians
We review studies from our laboratories using different molecular tools to characterize the ancestry of Brazilians in reference to their Amerindian, European and African roots. Initially we used uniparental DNA markers to investigate the contribution of distinct Y chromosome and mitochondrial DNA lineages to present-day populations. High levels of genetic ad
Brazilian Journal of Medical and Biological Research. Publicado em: 11/09/2009
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8. Haptoglobin gene subtypes in three Brazilian population groups of different ethnicities
Haptoglobin is a plasma hemoglobin-binding protein that limits iron loss during normal erythrocyte turnover and hemolysis, thereby preventing oxidative damage mediated by iron excess in the circulation. Haptoglobin polymorphism in humans, characterized by the Hp*1 and Hp*2 alleles, results in distinct phenotypes known as Hp1-1, Hp2-1 and Hp2-2, whose frequen
Genetics and Molecular Biology. Publicado em: 26/06/2009
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9. Analysis of the CCR5 gene coding region diversity in five South American populations reveals two new non-synonymous alleles in Amerindians and high CCR5*D32 frequency in Euro-Brazilians
The CC chemokine receptor 5 (CCR5) molecule is an important co-receptor for HIV. The effect of the CCR5*D32 allele in susceptibility to HIV infection and AIDS disease is well known. Other alleles than CCR5*D32 have not been analysed before, neither in Amerindians nor in the majority of the populations all over the world. We investigated the distribution of t
Genetics and Molecular Biology. Publicado em: 16/01/2009
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10. Infecção pelo herpesvírus 8 humano (HHV-8) em populações indígenas e não indígenas da Amazônia brasileira / Human herpesvirus-8 infection in amerindian and non-amerindian populations in the brazilian Amazon region
Human herpes virus type 8 (HHV-8) is hyperendemic in Amerindian populations, but its modes of transmission are unknown. Objectives: 1. Study the Human Herpesvirus-8 Infection and Oral Shedding in Amerindian and Non-Amerindian Populations in the Brazilian Amazon Region. 2. Methods: Antibodies against either HHV-8 latency-associated nuclear antigen (LANA) or H
Publicado em: 2009
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11. Estudo epidemiológico da infecção por herpesvírus 8 humano (HHV-8) em população indígena da Amazônia brasileira / Epidemiological study of Human herpesvirus 8 infection (HHV-8) in the Amerindian population from Brazilian Amazon
The human herpesvirus 8 (HHV-8) is endemic in Africa and Amerindian populations from Amazon region. The infection in those populations occurs during childhood and, in Africa, involves a close contact in intrafamilial environment. Several studies confirm the geographical distribution of different subtypes of HHV-8, and the subtype E is typical of the Amerindi
Publicado em: 2009
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12. Genética de populações e reinterpretação da história demográfica de remanescentes de quilombos: uma comparação entre três populações do nordeste brasileiro
The remanescentes de quilombos are multiethnic societies whose origins are related to the presence of African slaves in Brazil. The demographic history of these populations has been studied using historical, demographic, ethnographic and genetic sources. The present work aims to evaluate the origin and the impact of recent and ancient waves of immigration up
Publicado em: 2009