Androgen Receptor
Mostrando 1-12 de 354 artigos, teses e dissertações.
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1. Clinical and surgical assistance in prostate cancer during the COVID-19 Pandemic: implementation of assistance protocols
ABSTRACT Purpose: Propose an approach of prostate cancer (PCa) patients during COVID-19 pandemic. Material and Methods: We conducted a review of current literature related to surgical and clinical management of patients during COVID-19 crisis paying special attention to oncological ones and especially those suffering from PCa. Based on these publications a
Int. braz j urol.. Publicado em: 2020-07
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2. Association between decreased expression of estrogen receptor alpha, androgen receptor and phosphatase and tensin homolog immunoexpression in the canine prostate
RESUMO: A glândula prostática canina é um órgão dependente de hormônio, e o desequilíbrio na expressão dos receptores de estrógeno e andrógeno estão diretamente associados com o desenvolvimento de diferentes doenças. Devido à falta de informação sobre o comportamento desses receptores no câncer prostático canino (PC), este estudo tem por obj
Pesq. Vet. Bras.. Publicado em: 2019-01
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3. Stanozolol promotes osteogenic gene expression and apposition of bone mineral in vitro
Abstract Stanozolol (ST) is a synthetic androgen with high anabolic potential. Although it is known that androgens play a positive role in bone metabolism, ST action on bone cells has not been sufficiently tested to support its clinical use for bone augmentation procedures. Objective: This study aimed to assess the effects of ST on osteogenic activity and ge
J. Appl. Oral Sci.. Publicado em: 08/11/2018
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4. Androgen insensitivity syndrome: a review
ABSTRACT Androgenic insensitivity syndrome is the most common cause of disorders of sexual differentiation in 46,XY individuals. It results from alterations in the androgen receptor gene, leading to a frame of hormonal resistance, which may present clinically under 3 phenotypes: complete (CAIS), partial (PAIS) or mild (MAIS). The androgen receptor gene has 8
Arch. Endocrinol. Metab.. Publicado em: 2018-03
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5. Hypothalamic transcriptional expression of the kisspeptin system and sex steroid receptors differs among polycystic ovary syndrome rat models with different endocrine phenotypes
OBJECTIVES: Polycystic ovary syndrome is a heterogeneous endocrine disorder that affects reproductive-age women. The mechanisms underlying the endocrine heterogeneity and neuroendocrinology of polycystic ovary syndrome are still unclear. In this study, we investigated the expression of the kisspeptin system and gonadotropin-releasing hormone pulse regulator
Clinics. Publicado em: 2017-08
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6. Analyzing gene expression profiles in dilated cardiomyopathy via bioinformatics methods
Dilated cardiomyopathy (DCM) is characterized by ventricular dilatation, and it is a common cause of heart failure and cardiac transplantation. This study aimed to explore potential DCM-related genes and their underlying regulatory mechanism using methods of bioinformatics. The gene expression profiles of GSE3586 were downloaded from Gene Expression Omnibus
Braz J Med Biol Res. Publicado em: 10/10/2016
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7. The testis of the mice C57/BL6 offspring in adulthood have alterations due to maternal caffeine consumption
PURPOSE: To investigate the effects of the maternal caffeine consumption during pregnancy to adult male testis mice offspring. METHODS: Twenty pregnant mice were divided into control group (c) and caffeine group (cf). dams received daily saline or 20 mg/kg of caffeine subcutaneously. Male offspring were monitored daily until 13th week. The testis were
Acta Cir. Bras.. Publicado em: 2014-01
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8. Five-alpha Reductase Inhibitor Influences Expression of Androgen Receptor and HOXB13 in Human Hyperplastic Prostate Tissue
Objectives Five-alpha reductase inhibitors (5ARIs) are known as chemopreventive agents in prostate cancer with a risk of high-grade disease. This study evaluated the effects of 5ARI on androgen receptor (AR) and proteins involved in prostate cell growth such as HOXB13 expression in human prostate tissue and LNCaP prostate cancer cells. Materials and Method
Int. braz j urol.. Publicado em: 2013-12
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9. Regressão prostática pós-castração : caracterização das alterações causadas pela privação androgênica e alta dose de 17ß- estradiol / Prostatic regression after castration : characterization of changes by androgen deprivation and high dose 17ß- estradiol
O desenvolvimento, a fisiologia e o câncer de próstata dependem de balanços entre os níveis de andrógenos e estrógenos, que agem via receptor de andrógenos (AR) e receptores de estrógeno (ER alfa e ER beta ), respectivamente. Sabe-se que a cinética de morte das células epiteliais da próstata ventral de ratos (PV) após castração (grupo Cas), adm
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 29/02/2012
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10. Morfofisiologia do sistema genital masculino de ratos púberes e adultos após privação androgênica durante a pré-puberdade / Morphophysiology of male reproductive system of adult and pubertal rats after androgen deprivation during prepuberty
Endocrine disrupters are chemicals that can act as agonists or antagonists of endogenous hormones, interfering with the homeostasis of the organism. Since the endocrine system plays a critical role in the development and function of the male reproductive system, this is an especially vulnerable target of potential endocrine perturbations. The literature pres
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 06/02/2012
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11. Androgen receptor CAG polymorphism and the risk of benign prostatic hyperplasia in a Brazilian population
Benign prostatic hyperplasia (BPH) is a very frequent age-related proliferative abnormality in men. Polymorphic CAG repeat in the androgen receptor (AR) can alter transactivation of androgen-responsive genes and potentially influence BPH risk. We investigated the association between CAG repeat length and risk of BPH in a case-control study of a Brazilian pop
International braz j urol. Publicado em: 2012-06
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12. Ações da epitestosterona através de um mecanismo de membrana em células de Sertoli : implicações no desenvolvimento sexual
Introduction: Epitestosterone is the 17¿-epimer of testosterone. It seems to possess an antiandrogenic activity, as well as a neuroprotective effect. The mechanism of action of epitestosterone has not been elucidated. Objective: The aim of this work is to investigate the non-classical effect of epitestosterone on the membrane of Sertoli cells from testis of
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 2012