Angiotensinogen
Mostrando 1-12 de 105 artigos, teses e dissertações.
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1. Polymorphisms of the renin-angiotensin system are not associated with overweight and obesity in a general adult population
ABSTRACT Objective The increased prevalence of obesity and associated comorbidities, such as cardiovascular and metabolic diseases, has gained attention worldwide, and the renin-angiotensin system (RAS) has been pointed out as a possible link. Thus, the present study aimed to verify the possible association between angiotensinogen (AGT) or angiotensin-conv
Arch. Endocrinol. Metab.. Publicado em: 29/07/2019
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2. Resveratrol inhibits the intracellular calcium increase and angiotensin/endothelin system activation induced by soluble uric acid in mesangial cells
Resveratrol (Resv) is natural polyphenol found in grapes. This study evaluated the protective effect of Resv against the effects of uric acid (UA) in immortalized human mesangial cells (ihMCs). ihMCs were preincubated with Resv (12.5 µM) for 1 h and treated with UA (10 mg/dL) for 6 or 12 h. The intracellular calcium concentration [Ca2+]i was quantified by f
Braz J Med Biol Res. Publicado em: 24/10/2014
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3. Association of T174M polymorphism of angiotensinogen gene with essential hypertension: a meta-analysis
The association between T174M polymorphism of angiotensinogen gene and essential hypertension risk remains controversial. We herein performed a meta-analysis to achieve a reliable estimation of their relationship. All the studies published up to May 2013 on the association between T174M polymorphism and essential hypertension risk were identified by searchin
Genet. Mol. Biol.. Publicado em: 2014-09
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4. Exaggerated blood pressure response during the exercise treadmill test as a risk factor for hypertension
Exaggerated blood pressure response (EBPR) during the exercise treadmill test (ETT) has been considered to be a risk factor for hypertension. The relationship of polymorphisms of the renin-angiotensin system gene with hypertension has not been established. Our objective was to evaluate whether EBPR during exercise is a clinical marker for hypertension. The s
Braz J Med Biol Res. Publicado em: 19/04/2013
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5. Efeitos sequenciais do treinamento aeróbio sobre o sistema renina-angiotensina em núcleos autonômicos de ratos normotensos e hipertensos. / Sequential effects of aerobic training on the renin-angiotensin system in autonomic nuclei of normotensive and hipertensive rats.
The aerobic training (T) for 12 weeks was effective in reducing the mRNA of angiotensinogen(AGT) in NTS of SHR. We evaluate in SHR and WKY time-course changes of T on blood pressure, heart rate, AGT and AT1 mRNA and protein (PVN, NTS and RVL). WKY and SHR were T for 0,1,2,4,8 or 12 weeks, the baseline BP and HR were recorded and mRNA(RT-PCR) and Immunofluore
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 23/01/2012
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6. Alterations in the Renin-Angiotensin System in the contralateral carotid artery after balloon catheter injury / Alterações do Sistema Renina-Angiotensina na artéria carótida contralateral à lesão por cateter balão
Fifteen days after balloon catheter injury Emax of Ang II was increased in the contralateral artery as compared to values obtained in arteries from intact animals. This increase in Ang II Emax was not modified in the absence of the endothelium. The morphological and morphometric characteristics in the contralateral artery were not altered as compared to cont
Publicado em: 2010
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7. Efeitos da obesidade no sistema calicreína-cininas: estudo dos receptores b1 e b2 de cininas em tecido adiposo humano e murino. / Obesity, Leptin and Renin-Angiotensin System: Role on blood pressure control and autonomic regulation in ob/ob and db/db mice.
The leptin deficient ob/ob mice are insulin resistant and obese. However, the control of blood pressure in this model is not well defined. The goal of this study was to evaluate the role of leptin and the renin-angiotensin system (RAS) in the cardiovascular abnormalities observed in obesity using a model lacking leptin. Leptin is a hormone related to metabol
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 26/08/2009
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8. Evaluation of gene expression and polymorphisms of interleukin 6, the potassium channel voltage-dependent subunit subfamily E 5 and angiotensinogen in the incidence of atrial fibrillation post-surgical myocardial revascularization / Avaliação da expressão gênica e de polimorfismos da interleucina 6, do canal de potássio voltagem-dependente subfamília E subunidade 5 e angiotensinogênio na incidência da fibrilação atrial pós-operatória em revascularização cirúrgica do miocárdio
Estima-se que mais de 800.000 cirurgias cardíacas de revascularização do miocárdio por ano são realizadas no mundo. Nesta intervenção terapêutica uma das complicações mais comuns é a fibrilação atrial, que esta intimamente relacionada com aumento de risco de morbidade e mortalidade pós-operatória. Os fatores determinantes desta manifestação
Publicado em: 2009
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9. Characterization of a local renin-angiotensin system in the rat gingival tissue / Caracterização de um sistema renina-angiotensina local no tecido gengival de rato
Systemic renin-angiotensin system (RAS) promotes the plasmatic production of angiotensin (Ang) II, which acts through the interaction with specific receptors. The concept of this classic circulating RAS has been modified since there is growing evidence that local systems in various tissues and organs are capable of generating angiotensins independently of th
Publicado em: 2008
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10. Analysis of renin-angiotensin-aldosterone system gene polymorphisms in resistant hypertension
Essential hypertension is a disease multifactorially triggered by genetic and environmental factors. The contribution of genetic polymorphisms of the renin-angiotensin-aldosterone system and clinical risk factors to the development of resistant hypertension was evaluated in 90 hypertensive patients and in 115 normotensive controls living in Southwestern Braz
Brazilian Journal of Medical and Biological Research. Publicado em: 2007-03
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11. Cardiac mass and left ventricular function in a sample of the Brazilian population: candidate genes / Massa cardíaca e função do ventrículo esquerdo em amostra da população brasileira: genes candidatos
Introduction: Left ventricular hypertrophy is an important risk factor for cardiovascular morbidity and mortality. Its association with the reninangiotensin system genetic variants is controversial. Objectives: To assess the association between left ventricular mass, left ventricle systolic and diastolic functions, and polymorphisms of the insertion/deletion
Publicado em: 2006
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12. Caracterização da participação do sistema renina-angiotensina na cardiomiopatia induzida por hiperatividade simpática / Characterization of renin-angiotensin system in cardiomyopathy induced by sympathetic hyperactivity
We have recently reported that disruption of both alfa2A and alfa2C adrenergic receptor subtypes (KO) in mice leads to sympathetic hyperactivity with evidence of heart failure (HF) by seven months (mo) of age. In the present study, we have performed the phenotypical characterization on KO mice at three and seven month of age. In addition, we evaluated the ef
Publicado em: 2006