Animal Heart Failure
Mostrando 1-12 de 49 artigos, teses e dissertações.
-
1. Effects of gene therapy on cardiovascular symptoms of lysosomal storage diseases
Abstract Lysosomal storage diseases (LSDs) are inherited conditions caused by impaired lysosomal function and consequent substrate storage, leading to a range of clinical manifestations, including cardiovascular disease. This may lead to significant symptoms and even cardiac failure, which is an important cause of death among patients. Currently available tr
Genet. Mol. Biol.. Publicado em: 23/05/2019
-
2. Exercise training on cardiovascular diseases: Role of animal models in the elucidation of the mechanisms
Abstract Cardiovascular diseases, which include hypertension, coronary artery disease/myocardial infarction and heart failure, are one of the major causes of disability and death worldwide. On the other hand, physical exercise acts in the preventionand treatment of these conditions. In fact, several experiments performed in human beings have demonstrated the
Motriz: rev. educ. fis.. Publicado em: 02/05/2017
-
3. Cor triatriatum sinister e hipertensão arterial pulmonar secundária em cão
This paper describes the occurrence of cor triatriatum sinister, a rare cardiac malformation in dogs, associated with pulmonary edema and pulmonary hypertension in a 5-year-old Poodle female with history of acute dyspnea and cyanosis. The animal presented acute respiratory failure, heart failure with low cardiac output, progressing to acute tubular necrosis
Arq. Bras. Med. Vet. Zootec.. Publicado em: 2014-02
-
4. The effect of beta-blockade on myocardial remodelling in Chagas' cardiomyopathy
OBJECTIVE: Chagas' disease has spread throughout Latin America because of the high rate of migration among these countries. Approximately 30% of Chagas' patients will develop cardiomyopathy, and 10% of these will develop severe cardiac damage leading to heart failure. Beta-blockade improves symptoms and survival in heart failure patients; however, its effica
Clinics. Publicado em: 2012-09
-
5. Determinantes da fraqueza e propriedades contráteis da musculatura inspiratória na insuficiência cardíaca
The inspiratory muscle weakness may be present in 30-50% of outpatients with chronic heart failure, with implications for the quality of life and prognosis. However, it is unclear what clinical and behavioral characteristics that would be associated with this dysfunction. Moreover, as are unclear the molecular mechanisms leading to dysfunction of the diaphra
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 2012
-
6. Aerobic exercise training in heart failure: impact on sympathetic hyperactivity and cardiac and skeletal muscle function
Heart failure is a common endpoint for many forms of cardiovascular disease and a significant cause of morbidity and mortality. Chronic neurohumoral excitation (i.e., sympathetic hyperactivity) has been considered to be a hallmark of heart failure and is associated with a poor prognosis, cardiac dysfunction and remodeling, and skeletal myopathy. Aerobic exer
Brazilian Journal of Medical and Biological Research. Publicado em: 2011-09
-
7. Remodeling in the ischemic heart: the stepwise progression for heart
Abstract Coronary artery disease is the leading cause of death in the developed world and in developing countries. Acute mortality from acute myocardial infarction (MI) has decreased in the last decades. However, the incidence of heart failure (HF) in patients with healed infarcted areas is increasing. Therefore, HF prevention is a major challenge to the hea
Brazilian Journal of Medical and Biological Research. Publicado em: 2011-09
-
8. Cell therapy in dilated cardiomyopathy: from animal models to clinical trials
Dilated cardiomyopathy can be the end-stage form and common denominator of several cardiac disorders of known cause, such as hypertensive, ischemic, diabetic and Chagasic diseases. However, some individuals have clinical findings, such as an increase in ventricular chamber size and impaired contractility (classical manifestations of dilated cardiomyopathy) e
Brazilian Journal of Medical and Biological Research. Publicado em: 2011-05
-
9. Ablação por radiofreqüência do ventrículo esquerdo no rato: um novo modelo de insuficiência cardíaca com tamanhos de infarto do miocárdio semelhantes e baixa mortalidade. / Left ventricle radio-frequency ablation in the rat: a new model of heart failure due to myocardial infarction homogeneous in size and low in mortality
O Infarto do Miocárdio (IM) em roedores é o modelo animal mais freqüentemente utilizado para reproduzir experimentalmente a Insuficiência Cardíaca Congestiva (ICC) de humanos. A oclusão cirúrgica da artéria coronária descendente anterior (ACDA) é o método mais tradicionalmente usado para obter o IM experimental há décadas. Este modelo é bem val
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 25/08/2010
-
10. Participação da isoforma proteína quinase C βII na insuficiência cardíaca / Involvement of protein kinase C βII in heart failure
Heart failure is a common endpoint for many forms of cardiovascular disease and a significant cause of morbidity and mortality worldwide. Protein kinase C isozymes emerge as important potential therapeutic targets in chronic cardiovascular disease. However, individual PKC isozymes play different roles in the pathogenesis of cardiac diseases. Here, we charact
Publicado em: 2009
-
11. Disfunção cardíaca em animal nocaute para o receptor do tipo 2 para bradicinina
The Kinins are important peptides concerning control of cardiovascular function. Their action mechanism depend on the activation of two distinct receptor, type 1 and 2 bradykinin receptor (B1R and B2R). They both are coupled to G protein, which are responsible to activate different intracellular pathways, involved in different cellular process. Their role in
Publicado em: 2009
-
12. Experimental model of heart failure in rabbits / Desenvolvimento de modelo experimental de insuficiencia cardiaca em coelhos
Introduction: The development of heart failure experimental models is important to better understanding of physiopathology and validation of new therapeutic strategies. Few previous reports compared the models within the same animal species. Objective: Development and standardization of heart failure experimental model in rabbits with two interventions. Mate
Publicado em: 2008