Antibacterials
Mostrando 1-12 de 32 artigos, teses e dissertações.
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1. Topical ophthalmic antimicrobials: unfulfilled demands and possibility of new investments in Brazil and in the United States
In general, topical ophthalmic drug products, especially those used for treating infections, present low effectiveness because of various reasons, from unfavorable drug physicochemical properties to physiological protective mechanisms of the eye. The fact is such group of products holds room for improvement, which could mean the development of better drugs o
Braz. J. Pharm. Sci.. Publicado em: 24/10/2019
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2. Milk quality parameters associated with the occurrence of veterinary drug residues in bulk tank milk
ABSTRACT Veterinary drug residues in bulk tank milk are important to all sectors of the dairy chain because they are one of the major factors which determine the safety of the final product. This study attempted to identify milk quality parameters that are associated with the occurrence of veterinary drug residues using multivariate principal component analy
Sci. agric. (Piracicaba, Braz.). Publicado em: 2017-06
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3. In silico Antibacterial Activity Modeling Based on the TOMOCOMD-CARDD Approach
In the recent times, the race to cope with the increasing multidrug resistance of pathogenic bacteria has lost much of its momentum and health professionals are grasping for solutions to deal with the unprecedented resistance levels. As a result, there is an urgent need for a concerted effort towards the development of new antimicrobial drugs to stay ahead i
J. Braz. Chem. Soc.. Publicado em: 2015-06
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4. Green and brown propolis: efficient natural biocides for the control of bacterial contamination of alcoholic fermentation of distilled beverage
This study aimed to evaluate the efficiency of natural biocides, brown and green propolis, for the control of bacterial contamination in the production of sugarcane spirit. The treatments consisted of brown and green propolis extracts, ampicillin, and a control and were assessed at the beginning and end of harvest season in ten fermentation cycles. In the mi
Food Sci. Technol. Publicado em: 2014-12
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5. Lack of effect of cell-wall targeted antibacterials on biofilm formation and antifungal susceptibility of Candidaspecies
O uso de cateter venoso central (CVC) e antibióticos de amplo espectro estão entre os principais fatores de risco para o desenvolvimento da candidemia em pacientes internados em unidades de terapia intensiva (UTI). É conhecido que alguns antibióticos aumentam a resistência das leveduras aos antifúngicos azólicos. Assim, o objetivo deste estudo foi ava
Braz. J. Pharm. Sci.. Publicado em: 2014-09
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6. Síntese e Avaliação Biológica de Derivados 4-Aminoquinolínicos e 4-Mercaptoquinolínicos
Este trabalho intitulado Síntese e Avaliação Biológica de Derivados 4-Aminoquinolínicos e 4-Mercaptoquinolínicos está dividido em duas partes e descreve a síntese de compostos quinolínicos acoplados a moléculas e/ou compostos heterocíclicos com atividade biológica. A primeira parte que trata da obtenção de derivados 4-aminoquinolínicos, aprese
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 16/07/2011
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7. Evaluation of the probiotic properties in broilers of Pichia pastoris and a recombinant Pichia pastoris containing the Clostridium perfringens fosfolipase C gene / Avaliação como probióticos para frangos de corte de Pichia pastoris e Pichia pastoris recombinante contendo o gene da fosfolipase C de Clostridium perfringens
Antibiotics used for the last decades as growth promoters for animals, were banned in several countries because of the risk of inducing the appearance of antibiotic resistant bacteria. Probiotics, live microorganisms that benefit health promoting the stability of the gut microbiota, are their most promising substitutes. The objective of this research was to
Publicado em: 2008
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8. Synthesis of 2-oxazolidinones with potential antibacterial activity from Morita-Baylis-Hillman adducts / Sintese de 2-oxazolidinonas com potencial atividade antibacteriana, a partir de adutos de Morita-Baylis-Hillman
Este trabalho teve como objetivo sintetizar e avaliar a atividade biológica de algumas 2-oxazolidinonas. As oxazolidinonas são compostos versáteis utilizados na preparação de uma série de outras classes de compostos e são largamente utilizados como auxiliares quirais em sínteses orgânicas assimétricas. Biologicamente são de grande importância por
Publicado em: 2007
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9. PurificaÃÃo e caracterizaÃÃo de antibacterianos de plantas do municÃpio de Lavras, MG. / Purification and identification of antibacterials from Lavras city plants.
Screening of 30 methanol extracts from plants collected in Lavras city (MG) was conducted using the agar diffusion method to identify antibacterial properties against Aeromonas hydrophila ATCC 7966, Bacillus subtilis ATCC 6633, Pseudomonas aeruginosa ATCC 27853 and Staphylococcus aureus ATCC 25923. It was observed that 13 of them presented antibacterial acti
Publicado em: 2006
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10. Introdução a modelagem molecular de fármacos no curso experimental de química farmacêutica
Molecular Modeling is an important tool in drug design and it is very useful to predict biological activity from a library of compounds. A wide variety of computer programs and methods have been developed to visualize the tridimensional geometry and calculate physical properties of drugs. In this work, we describe a practical approach of molecular modeling a
Química Nova. Publicado em: 2003-05
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11. Efeito do diclofenaco sodico sobre a concentração serica e tecidual da amoxicilina e sobre a infecção estafilococica : estudo in vivo, em ratos
O presente trabalho teve por objetivo observar o efeito da amoxicilina, do diclofenaco sódico e da associação de ambos sobre a infecção estafilocócica induzida em tecidos granulomatosos, em ratos. Também foram avaliadas as concentrações sérica e teciduais da amoxicilina, observando o efeito da associação do diclofenaco sódico sobre as mesmas. Tr
Publicado em: 2000
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12. Use of plastic spot-plates for in vitro assessment of antibacterials.