Antifungal Agent
Mostrando 1-12 de 330 artigos, teses e dissertações.
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1. Extracts of the Native Brazilian Tree Garcinia gardneriana Inhibit Urediniospore Germination of Coffee Leaf Rust Fungus
The fungal Hemileia vastatrix is the causal agent of coffee leaf rust, one of the worst and devastating disease in coffee cultures worldwide. As a result of our research on natural products for the development of novel agrochemicals, we found that the hexane extract from leaves of the Brazilian medicinal plant Garcinia gardneriana, at 500 μg mL-1, inhibited
Journal of the Brazilian Chemical Society. Publicado em: 2022
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2. Antifungal potential of essential oils from two varieties of Citrus sinensis (lima orange and bahia navel orange) in postharvest control of Rhizopus stolonifer (Ehrenb.: Fr.) Vuill.
Abstract Brazil, the world’s largest citros producer, yields around 19 million tons per year and exports most part of its production as orange juice. Essential oils (EOs) extracted from leaves, fruit and flowers of many species of the genus Citrus have been widely used as the result of their promising bioactivities. The fungus Rhizopus stolonifer (Ehrenb.)
Food Sci. Technol. Publicado em: 2020-12
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3. Antifungal Efficacy of Amphotericin B in Candida Albicans Endocarditis Therapy: Systematic Review
Abstract Introduction: Although it is the most common agent among the fungal causes of endocarditis, Candida albicans endocarditis is rare. Objective: To evaluate the efficacy of amphotericin B in the treatment of C. albicans endocarditis beyond a systematic review. Data search: Articles in English, Spanish and Portuguese, conducted in the following datab
Braz. J. Cardiovasc. Surg.. Publicado em: 2020-10
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4. Combretastatin A-4: The Antitubulin Agent that Inspired the Design and Synthesis of Styrene and Spiroisatin Hybrids as Promising Cytotoxic, Antifungal and Antiviral Compounds
The design of a series of styrene and spiroisatin hybrids was based on the structure of combretastatin A-4 1. This library of 20 compounds were synthesized with the pharmacophoric units: 3,4,5-trimethoxy or/and 4-hydroxy-3-methoxy phenyl moities in their structure. Thereby, the libraries of β-nitrostyrenes 10a-10c, spiroisatin-dihydroquinolines 14a-14c, spi
J. Braz. Chem. Soc.. Publicado em: 2020-05
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5. Methodology Development and Validation of Amphotericin B Stability by HPLC-DAD
The high worldwide consumption of antibiotics and their complex impurity profiles has drawn the attention of the scientific community to the development and validation of stability methods for these drugs. Amphotericin B is an antibiotic that is a natural fermentation product of bacterium Streptomyces nodosus, used as a broad-spectrum antifungal agent, and i
J. Braz. Chem. Soc.. Publicado em: 2020-05
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6. Synergic effect of simvastatin in combination with amphotericin B against environmental strains of Cryptococcus neoformans from northeastern Brazil: a prospective experimental study
BACKGROUND: Statins are used as cholesterol-lowering drugs and may also have direct antimicrobial effects. OBJECTIVE: To evaluate synergic interactions between simvastatin and both amphotericin B and fluconazole, against environmental strains of Cryptococcus neoformans isolated from captive birds’ droppings. DESIGNAND SETTING: Experimental study cond
Sao Paulo Med. J.. Publicado em: 2020-02
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7. Interference of aqueous and ethanolic solutions of Adiantum latifolium Lam. (Pteridaceae) leaves on in vitro Ceratocystis cacaofunesta mycelial growth
RESUMO A espécie Ceratocystis cacaofunesta é o agente etiológico do mal-do-facão, patogenia caracterizada por danos irreversíveis no sistema vascular da planta. O controle da doença é difícil e a busca por soluções alternativas e econômicas é necessária. Sabe-se que os compostos das plantas medicinais possuem atividade microbiana e podem ser uma
Arq. Inst. Biol.. Publicado em: 02/12/2019
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8. In-Vitro Antibacterial and Antifungal Effects of High Levels of Chinese Star Anise
ABSTRACT This study investigated the in-vitro antibacterial and fungicidal activities of three crude extracts of Illicium verum (absolute methanol, 50% methanol and aqueous extracts) against two Gram-positive bacteria (Staphylococcus aureus and Listeria monocytogenes), two Gram-negative bacteria (Escherichia coli and Salmonella Arizona), and two fungi (Asper
Braz. J. Poult. Sci.. Publicado em: 11/11/2019
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9. Amphotericin-B and vancomycin-loaded chitosan nanofiber for antifungal and antibacterial application
In the present study, a mucoadhesive non-woven fiber mat (d= 116 nm) was fabricated by the electrospinning method using chitosan (80% Wt), polyethylene oxide (10% Wt), cysteine (4% Wt) and drugs (6% Wt), respectively. In addition, a comparative study was conducted to define effect of drugs and mucoadhesive agent on the nanofiber formation. FTIR, SEM, DSC and
Braz. J. Pharm. Sci.. Publicado em: 09/09/2019
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10. Saline extract from Malpighia emarginata DC leaves showed higher polyphenol presence, antioxidant and antifungal activity and promoted cell proliferation in mice splenocytes.
Abstract: Currently, the research of new natural compounds with biological potential demonstrates great ethnopharmacological importance. In this study, we evaluated the biological properties promoted by saline extract from Malpighia emarginata DC leaves, whose objective is to evaluate the antioxidant, antimicrobial and cytotoxicity potential. Phytochemical c
An. Acad. Bras. Ciênc.. Publicado em: 08/04/2019
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11. Anadenanthera Colubrina vell Brenan: anti-Candida and antibiofilm activities, toxicity and therapeutical action
Abstract: We evaluated the antifungal and antibiofilm potential of the hydroalcoholic extract of bark from Anadenanthera colubrina (vell.) Brenan, known as Angico, against Candida spp. Antifungal activity was evaluated using the microdilution technique through the Minimum Inhibitory and Fungicide Concentrations (MIC and MFC). The antibiofilm potential was te
Braz. oral res.. Publicado em: 04/04/2019
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12. Variability in the clinical distributions of Candida species and the emergence of azole-resistant non-Candida albicans species in public hospitals in the Midwest region of Brazil
Abstract INTRODUCTION Incidence and antifungal susceptibility of Candida spp. from two teaching public hospitals are described. METHODS The minimum inhibitory concentrations of fluconazole, voriconazole, itraconazole, and amphotericin B were determined using Clinical Laboratory Standard Institute broth microdilution and genomic differentiation using PCR.
Rev. Soc. Bras. Med. Trop.. Publicado em: 2017-12