Antigen Receptors
Mostrando 1-12 de 908 artigos, teses e dissertações.
-
1. Up-regulation of RIP1 and IPS-1 in chronic HBV infected patients
Abstract IPS-1 and RIP1 are the main downstream molecules of RIG1 and MDA5, as intracytoplasmic receptors, which are the main receptors involved in recognition of internal and external viral double-stranded RNA. In this project, mRNA levels of IPS-1 and RIP1 were investigated in the peripheral blood immune cells of chronic hepatitis B (CHB) patients. IPS-1 a
Genet. Mol. Biol.. Publicado em: 19/08/2019
-
2. Innate immunity and HPV: friends or foes
Most human papillomavirus infections are readily cleared by the host immune response. However, in some individuals, human papillomavirus can establish a persistent infection. The persistence of high-risk human papillomavirus infection is the major risk factor for cervical cancer development. These viruses have developed mechanisms to evade the host immune sy
Clinics. Publicado em: 11/10/2018
-
3. Innate immunity and effector and regulatory mechanisms involved in allergic contact dermatitis
Abstract: Skin's innate immunity is the initial activator of immune response mechanisms, influencing the development of adaptive immunity. Some contact allergens are detected by Toll-like receptors (TLRs) and inflammasome NLR3. Keratinocytes participate in innate immunity and, in addition to functioning as an anatomical barrier, secrete cytokines, such as TN
An. Bras. Dermatol.. Publicado em: 2018-03
-
4. Adiponectin inhibits oxidization-induced differentiation of T helper cells through inhibiting costimulatory CD40 and CD80
Adiponectin is a multifunctional adipokine that has several oligomeric forms in the blood stream, which broadly regulates innate and acquired immunity. Therefore, in this study, we aimed to observe the differentiation of T helper (Th) cells and expression of costimulatory signaling molecules affected by adiponectin. The mRNA and protein expression levels of
Braz J Med Biol Res. Publicado em: 15/05/2017
-
5. Phytohemagglutinin improves the development and ultrastructure of in vitro-cultured goat (Capra hircus) preantral follicles
The objective this study was to determine the effect of phytohemagglutinin (PHA) on survival, growth and gene expression in caprine secondary follicles culturedin vitro. Secondary follicles (∼0.2 mm) were isolated from the cortex of caprine ovaries and cultured individually for 6 days in α-MEM+ supplemented with PHA (0, 1, 10, 50, 100, or 200 µg/mL). Aft
Braz J Med Biol Res. Publicado em: 19/03/2013
-
6. Pathophysiology of bacterial infection of the central nervous system and its putative role in the pathogenesis of behavioral changes
Invasion of the central nervous system (CNS) by microorganisms is a severe and frequently fatal event during the course of many infectious diseases. It may lead to deafness, blindness, cerebral palsy, hydrocephalus, cognitive impairment or permanent neurological dysfunction in survivors. Pathogens can cross the blood-brain barrier by transcellular migration,
Rev. Bras. Psiquiatr.. Publicado em: 2013-03
-
7. Receptores de estrógeno e progesterona, Ki67, Bcl-2 E Cox-2 em pólipos endometriais de mulheres na pré e pós-menopausa e associação com a obesidade, = : Estrogen and progesterone receptors, Ki67, Bcl-2 and Cox-2 markers in benign endometrial polyps in pre and postmenopausal women and their association with obesity / Estrogen and progesterone receptors, Ki67, Bcl-2 and Cox-2 markers in benign endometrial polyps in pre and postmenopausal women and their association with obesity
Introdução: A prevalência de obesidade tem aumentado em todo o mundo e hoje já representa um problema de saúde pública. Na população feminina, seu aumento ocorre principalmente nos anos próximos da transição para menopausa. O aumento de peso representa um risco para diversas comorbidades, dentre elas um importante fator de risco para patologia end
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 06/11/2012
-
8. Leishmania amazonensis prejudica resposta de células dendríticas via inibição da expressão de CD40 mediada por ectonucleotidases e pela ativação do receptor de adenosina A2B / Leishmania amazonensis prejudica resposta de células dendríticas via inibição da expressão de CD40 mediada por ectonucleotidases e pela ativação do receptor de adenosina A2B
Leishmania infections can result in a wide spectrum of clinical manifestations, and the outcome of disease is determined by parasite species and the host immune response. Dendritic cells play an essential role in the modulation of immune response including during Leishmania infection. Extracellular-ATP exhibits pro-inflammatory properties whereas adenosine i
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 24/02/2012
-
9. Doenças reumatológicas autoimunes e sua associação com os genes killer immunoglobulin-like receptors
Os genes Killer Immunoglobulin-like Receptors (KIR) expressam-se como receptores que estimulam ou inibem as células Natural Killer (NK). As células NK fazem parte da imunidade inata e através de seus receptores KIR identificam células-alvo que apresentam moléculas HLA (Human Leukocyte Antigen) modificadas ou diferentes, induzindo à sua lise. Os recepto
Revista Brasileira de Reumatologia. Publicado em: 2011-08
-
10. Importance of killer immunoglobulin-like receptors in allogeneic hematopoietic stem cell transplantation
Hematopoietic stem cell transplantation is the treatment of choice for many hematologic diseases, such as multiple myeloma, bone marrow aplasia and leukemia. Human leukocyte antigen (HLA) compatibility is an important tool to prevent post-transplant complications such as graft rejection and graft-versus-host disease, but the high rates of relapse limit the s
Revista Brasileira de Hematologia e Hemoterapia. Publicado em: 2011
-
11. Chagas' disease and Duffy antigen/receptor for chemokine (DARC): a mini-review
Duffy gene (FY) codifies the transmembrane glycoprotein Duffy (gp-Fy) of 35 to 43 kDa which is moderately immunogenic. This glycoprotein is polymorphic, and constitutes the antigens of the Duffy histo-blood system which were designated receptors for chemokines and denominated DARC (Duffy antigen/receptor for chemokine). This receptor has an important role in
Journal of Venomous Animals and Toxins including Tropical Diseases. Publicado em: 2011
-
12. Estudo de polimorfismos dos genes KIR e HLA em pacientes com câncer de próstata
O câncer de próstata é o segundo câncer mais comum entre homens, uma vez que tanto a incidência como a mortalidade aumentam exponencialmente após a idade de 50 anos. As células Natural Killer (NK) fazem parte do sistema imune inato e reconhecem moléculas de HLA de classe I na célula alvo, através de seus receptores de membrana, chamados killer immu
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 2011