Anxiogenic Effect
Mostrando 1-12 de 20 artigos, teses e dissertações.
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1. Anxiolytic-like and proneurogenic effects of Trichilia catigua ethyl-acetate fraction in mice with cerebral ischemia
Abstract Trichilia catigua A. Juss., Meliaceae, known as "catuaba" in Brazil, has been popularly used as a tonic for fatigue, impotence and memory deficits. Previously, we have demonstrated that T. catigua ethyl-acetate fraction exerted antidepressive-like effects in mice. Affective-like symptoms are also well recognized outcome of cerebral ischemia in clini
Rev. bras. farmacogn.. Publicado em: 09/12/2019
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2. Can anxiety increase tremors in patients with Parkinson’s disease? An experimental model
Abstract Background Among non-motor symptoms of Parkinson’s disease (PD), anxiety occurs in up to 67% of patients. Clinically, PD patients report worsening of tremors in anxiogenic situations. Objective The aim of this study was to evaluate the association between motor symptoms and anxiety in PD patients and compare their performances with those of he
Arch. Clin. Psychiatry (São Paulo). Publicado em: 2017-08
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3. Neuropharmacological and genotoxic evaluation of ethanol extract from Erythrina falcata leaves, a plant used in Brazilian folk medicine
The aim of the present study was to determine neurobehavioral and genotoxic activities of ethanol extract of Erythrina falcata Benth., Fabaceae, leaves on rats. Animals were treated with ethanol extract of E. falcata (100, 300 or 500 mg/kg; i.p.) and the open field and elevated plus-maze tasks were used as behavioral models to investigate a possible effect o
Rev. bras. farmacogn.. Publicado em: 25/02/2013
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4. Dorsal periaqueductal gray stimulation facilitates anxiety-, but not panic-related, defensive responses in rats tested in the elevated T-maze
The escape response to electrical or chemical stimulation of the dorsal periaqueductal gray matter (DPAG) has been associated with panic attacks. In order to explore the validity of the DPAG stimulation model for the study of panic disorder, we determined if the aversive consequences of the electrical or chemical stimulation of this midbrain area can be dete
Braz J Med Biol Res. Publicado em: 2012-11
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5. Effects of chronic corticosterone and imipramine administration on panic and anxiety-related responses
It is known that chronic high levels of corticosterone (CORT) enhance aversive responses such as avoidance and contextual freezing. In contrast, chronic CORT does not alter defensive behavior induced by the exposure to a predator odor. Since different defense-related responses have been associated with specific anxiety disorders found in clinical settings, t
Brazilian Journal of Medical and Biological Research. Publicado em: 2011-10
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6. Reversal of CRF- and stress-induced anorexia by an ayurvedic formulation
Trikatu churna is one of the commonly used Ayurvedic formulations in the traditional system of medicine in India for the treatment of agnimandya, i.e. anorexia. Trikatu contains equal amounts of finely powdered rhizomes of Zingiber officinale Roscoe (Zingiberaceae) and fruits of Piper longum L. and Piper nigrum L. (Piperaceae). The chief objective of the stu
Revista Brasileira de Farmacognosia. Publicado em: 09/09/2011
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7. Differential behavioral outcomes of 3,4-methylenedioxymethamphetamine (MDMA-ecstasy) in anxiety-like responses in mice
Anxiolytic and anxiogenic-like behavioral outcomes have been reported for methylenedioxymethamphetamine (MDMA or ecstasy) in rodents. In the present experiment, we attempted to identify behavioral, hormonal and neurochemical outcomes of MDMA treatment to clarify its effects on anxiety-related responses in 2-month-old Balb/c male mice (25-35 g; N = 7-10 mice/
Brazilian Journal of Medical and Biological Research. Publicado em: 2011-05
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8. Efeitos da privação de sono paradoxal na nocicepção e ansiedade em ratos / Effects of paradoxical sleep deprivation in rats on nociception and anxiety
Paradoxical sleep deprivation (PSD) causes several neurochemical and behavioral changes related to alterations in neurotransmitters systems. Increased responses to nociceptive stimuli have been reported in animals deprived of this phase of sleep. The commonly used methods of PSD have been linked to the generation of anxiety in animals, and hyperalgesia could
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 22/12/2010
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9. Antidepressant- and anxiogenic-like effects of acute 5-HT2C receptor activation in rats exposed to the forced swim test and elevated plus maze
This study investigated the behavioral effects in the forced swim test (FST) and the elevated plus-maze (EPM) of acute administration of WAY 161503 ([4aR]-8,9-dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5[6 H]-one), a selective 5-HT2C receptor agonist with putative antidepressant-like properties. Fifteen minutes after intraperitoneal (i.p.) inj
Psychology & Neuroscience. Publicado em: 2010-12
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10. Role of nitric oxide in the periaqueductal gray in defensive behavior in mice: influence of prior local N-methyl-D-aspartate receptor activation and aversive condition
Glutamate N-methyl-D-aspartate (NMDA) receptor activation within the dorsal column of the periaqueductal gray (dPAG) leads to antinociceptive, autonomic, and behavioral responses characterized as the fear reaction. Activation of NMDA receptors in the brain increases nitric oxide (NO) synthesis, and NO has been proposed to be a mediator of the aversive action
Psychology & Neuroscience. Publicado em: 2010-06
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11. Effects of contextual fear conditioning and pentylenetetrazol on panic-like reactions induced by dorsal periaqueductal gray stimulation with N-methyl-D-aspartate
Electrical or chemical stimulation of the dorsal periaqueductal gray (DPAG) has been accepted as an animal model of panic attacks. This study investigates the influence of anticipatory anxiety in the occurrence of panic-like behavior induced by N-methyl-D-aspartate (NMDA) microinjection into the DPAG of rats. Behavioral (i.e., contextual fear conditioning) a
Psychology & Neuroscience. Publicado em: 2010-06
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12. Efeito do pentilenotetrazol e do midazolam na aquisição e na expressão da resposta defensiva de ratos submetidos ao condicionamento olfatório de medo
Pavlovian fear conditioning or first-order fear conditioning has been widely used to study the neuroanatomical, cellular and molecular basis of fear. This paradigm occurs when an emotionally neutral stimulus is presented in conjunction with an aversive unconditioned stimulus (US). After one or several pairings the stimulus, previously neutral, acquires the a
Publicado em: 2009