Apcc
Mostrando 1-12 de 36 artigos, teses e dissertações.
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1. Grupos de pais-bebês nas creches como estratégia de promoção da saúde mental na primeira infância
Resumo O presente artigo tem como objetivo apresentar a estratégia do grupo interativo pais-bebês em creches como intervenção psicanalítica possível para a promoção da saúde mental na primeira infância no campo educativo. Trata-se de um desdobramento da pesquisa Metodologia IRDI – uma intervenção com educadores de creche a partir da psicanális
Educ. Pesqui.. Publicado em: 18/10/2018
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2. GERENCIAMENTO DE PONTOS CRÍTICOS EM SEGURANÇA DO TRABALHO BASEADO NA METODOLOGIA APPCC / MANAGEMENT OF CRITICAL POINTS IN THE SAFETY WORKING BASED ON HACCP METHODOLOGY
A metodologia de Análise de Perigos e Pontos Críticos de Controle (APPCC), em sua essência visa o controle microbiológico em alimentos. Atentando para os mecanismos de seu funcionamento, pesquisou-se a possível adaptação da mesma como ferramenta de apoio ao gerenciamento de riscos ocupacionais. Este trabalho propõe a adaptação dos fundamentos da me
Publicado em: 2009
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3. QUALITY CONTROL OF YOGURT INDUSTRIALIZATION WITHOUT CONSERVATION WITH THE APPLICATION OF THE APPCC TOOL / CONTROLE DA QUALIDADE DA INDUSTRIALIZAÇÃO DO IOGURTE SEM CONSERVANTE COM A APLICAÇÃO DA FERRAMENTA APPCC
With the purpose of verifying the quality of industrialization of yogurt without artifivcial preservatives with fruit pulp it was decided to use the Analysis of Risks and Critical Control Points, APPCC in SETREM agro industry. The work has started with an APPCC group first constitution were, hen in a second moment established the risks and ways of prevention
Publicado em: 2005
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4. Xenopus polo-like kinase Plx1 regulates XErp1, a novel inhibitor of APC/C activity
Metaphase-to-anaphase transition is a fundamental step in cell cycle progression where duplicated sister-chromatids segregate to the future daughter cells. The anaphase-promoting complex/cyclosome (APC/C) is a highly regulated ubiquitin-ligase that triggers anaphase onset and mitotic exit by targeting securin and mitotic cyclins for destruction. It was previ
Cold Spring Harbor Laboratory Press.
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5. Mad2 phosphorylation regulates its association with Mad1 and the APC/C
Improper attachment of the mitotic spindle to the kinetochores of paired sister chromatids in mitosis is monitored by a checkpoint that leads to an arrest in early metaphase. This arrest requires the inhibitory association of Mad2 with the anaphase promoting complex/cyclosome (APC/C). It is not known how the association of Mad2 with the kinetochore and the A
Oxford University Press.
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6. Regulation of the Anaphase-promoting Complex/Cyclosome by bimAAPC3 and Proteolysis of NIMA
Surprisingly, although highly temperature-sensitive, the bimA1APC3 anaphase-promoting complex/cyclosome (APC/C) mutation does not cause arrest of mitotic exit. Instead, rapid inactivation of bimA1APC3 is shown to promote repeating oscillations of chromosome condensation and decondensation, activation and inactivation of NIMA and p34cdc2 kinases, and a
The American Society for Cell Biology.
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7. The Schizosaccharomyces pombe dim1+ Gene Interacts with the Anaphase-Promoting Complex or Cyclosome (APC/C) Component lid1+ and Is Required for APC/C Function
The Schizosaccharomyces pombe dim1+ gene is required for entry into mitosis and for chromosome segregation during mitosis. To further understand dim1p function, we undertook a synthetic lethal screen with the temperature-sensitive dim1-35 mutant and isolated lid (for lethal in dim1-35) mutants. Here, we describe the temperature-sensitive lid1-6 mutant. At th
American Society for Microbiology.
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8. Mammalian Cdh1/Fzr mediates its own degradation
The Anaphase-Promoting Complex/Cyclosome (APC/C) ubiquitin ligase mediates degradation of cell cycle proteins during mitosis and G1. Cdc20/Fzy and Cdh1/Fzr are substrate-specific APC/C activators. The level of mammalian Cdh1 is high in mitosis, but it is inactive and does not bind the APC/C. We show that when Cdh1 is active in G1 and G0, its levels are consi
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9. Crystal Structure of the N-terminal Domain of Anaphase-promoting Complex Subunit 7*S⃞
Anaphase-promoting complex or cyclosome (APC/C) is an unusual E3 ubiquitin ligase and an essential protein that controls mitotic progression. APC/C includes at least 13 subunits, but no structure has been determined for any tetratricopeptide repeat (TPR)-containing subunit (Apc3 and -6-8) in the TPR subcomplex of APC/C. Apc7 is a TPR-containing subunit t
American Society for Biochemistry and Molecular Biology.
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10. Swm1/Apc13 Is an Evolutionarily Conserved Subunit of the Anaphase-Promoting Complex Stabilizing the Association of Cdc16 and Cdc27
The anaphase-promoting complex (APC/C) is a large ubiquitin-protein ligase which controls progression through anaphase by triggering the degradation of cell cycle regulators such as securin and B-type cyclins. The APC/C is an unusually complex ligase containing at least 10 different, evolutionarily conserved components. In contrast to APC/C's role in cell cy
American Society for Microbiology.
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11. The Apc5 Subunit of the Anaphase-Promoting Complex/Cyclosome Interacts with Poly(A) Binding Protein and Represses Internal Ribosome Entry Site-Mediated Translation
The anaphase-promoting complex/cyclosome (APC/C) is a multisubunit ubiquitin ligase that mediates the proteolysis of cell cycle proteins in mitosis and G1. We used a yeast three-hybrid screen to identify proteins that interact with the internal ribosome entry site (IRES) of platelet-derived growth factor 2 mRNA. Surprisingly, this screen identified Apc5, alt
American Society for Microbiology.
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12. The Arabidopsis Anaphase-Promoting Complex or Cyclosome: Molecular and Genetic Characterization of the APC2 Subunit
In yeast and animals, the anaphase-promoting complex or cyclosome (APC/C) is an essential ubiquitin protein ligase that regulates mitotic progression and exit by controlling the stability of cell cycle regulatory proteins, such as securin and the mitotic cyclins. In plants, the function, regulation, and substrates of the APC/C are poorly understood. To gain
American Society of Plant Biologists.