Apollon
Mostrando 1-4 de 4 artigos, teses e dissertações.
-
1. The Role of Apollon Gene Silencing on Viablity and Radiosensitivity of Cervical Cancer Hela Cells
Cervical cancer is the second common cause of cancer deaths in women worldwide. Radioresistancy of cancer is a principal cause of treatment impairing. Inhibitor of apoptosis proteins (IAPs) widely block apoptosis against apoptotic stimuli, including current chemo- and radiation therapies. Apollon, a membrane of IAP, can support cells against apoptosis and is
Braz. arch. biol. technol.. Publicado em: 06/05/2016
-
2. O crepÃsculo da tragÃdia: arte e platonismo na obra do jovem Nietzsche / Le crÃpuscule de la tragÃdie: art et platonisme dans l oeuvre du jeune Nietzsche
Investiga a obra filosÃfica do jovem Nietzsche, especialmente O nascimento da tragÃdia, na busca da compreensÃo de seus fundamentos crÃticos em relaÃÃo ao pensamento ocidental, marcado, fundamentalmente, pelo influxo do platonismo. Para a coleta de dados, utiliza-se pesquisa nas obras da juventude nietzschiana como tambÃm nas obras de Richard Wagner,
Publicado em: 2007
-
3. Nrdp1-mediated degradation of the gigantic IAP, BRUCE, is a novel pathway for triggering apoptosis
Degradation of certain inhibitor of apoptosis proteins (IAPs) appears to be critical in the initiation of apoptosis, but the factors that regulate their degradation in mammalian cells are unknown. Nrdp1/FLRF is a RING finger-containing ubiquitin ligase that catalyzes degradation of the EGF receptor family member, ErbB3. We show here that Nrdp1 associates wit
Nature Publishing Group.
-
4. The Birc6 (Bruce) gene regulates p53 and the mitochondrial pathway of apoptosis and is essential for mouse embryonic development
Baculoviral inhibitor of apoptosis repeat-containing (Birc)6 gene/BIRC6 (Bruce/APOLLON) encodes an inhibitor of apoptosis and a chimeric E2/E3 ubiquitin ligase in mammals. The physiological role of Bruce in antiapoptosis is unknown. Here, we show that deletion of the C-terminal half of Bruce, including the UBC domain, causes activation of caspases and apopto
National Academy of Sciences.