Arcaine
Mostrando 1-5 de 5 artigos, teses e dissertações.
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1. Arcaine-induced state-dependent memory involves opioid mechanisms in rats / ENVOLVIMENTO DO SISTEMA OPIÓIDE NA DEPENDÊNCIA DE ESTADO INDUZIDA PELA ARCAÍNA EM RATOS
Arcaine is a competitive antagonist of the polyamine binding site at the NMDA receptor which induces state-dependent recall. However, no study has addressed the involvement of other neurotransmitter/neuromodulators in arcaine-induced state dependency. The current study investigates whether the opioid system is involved in arcaine-induced state-dependent memo
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 02/03/2011
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2. POLIAMINERGIC AGENTS MODULATE CONTEXTUAL FEAR EXTINCTION IN RATS / AGENTES POLIAMINÉRGICOS MODULAM A EXTINÇÃO DO MEDO CONDICIONADO CONTEXTUAL EM RATOS
Polyamines, such as spermidine and spermine, have been reported to improve memory retention through the activation of N-methyl-D-aspartate receptors (NMDAr). However whether polyamine agonists and antagonists alter extinction remains unclear. In the current study, we investigated whether spermidine and polyamine antagonists that selectively block the NR2B su
Publicado em: 2009
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3. SYSTEMIC ADMINISTRATION OF SPERMIDINE AND ARCAINE ALTERS MEMORY OF THE INIBITORY AVOIDANCE TASK IN RATS: STATE DEPENDENCE INVOLVIMENT. / ADMINISTRAÇÃO SISTÊMICA DE ESPERMIDINA E ARCAÍNA ALTERA A MEMÓRIA DA TAREFA DE ESQUIVA INIBITÓRIA EM RATOS: ENVOLVIMENTO DA DEPENDÊNCIA DE ESTADO
The polyamines, putrescine, spermidine and spermine, are present in high concentrations in the central nervous system and, because of their policationic nature, they can interact with diverse cellular anionic targets (nucleic acids and proteins) and modulate the learning and memory by interacting with the polyamine binding site at N-methyl-D-aspartate recept
Publicado em: 2006
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4. SYSTEMIC ADMINISTRATION OF POLYAMINERGIC AGENTS MODULATE FEAR CONDITIONING IN RATS. / ADMINISTRAÇÃO SISTÊMICA DE AGENTES POLIAMINÉRGICOS MODULA A MEMÓRIA NA TAREFA DE MEDO CONDICIONADO EM RATOS
The polyamines, spermine, spermidine and putrescine, are a group of aliphatic amines that interact with diverse cellular targets such as nucleic acids and proteins. The polyamines may act as physiological modulators of N-methyl-D-aspartate (NMDA) receptors. The processes mediated by NMDA receptor include synaptic plasticity and formation of neural circuitry
Publicado em: 2006
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5. POLIAMINAS MODULAM A MEMÓRIA NAS TAREFAS DE MEDO CONDICIONADO E ESQUIVA INIBITÓRIA EM RATOS / POLYAMINES MODULATE MEMORY IN FEAR-CONDIDIONING AND INHIBITORY AVOIDANCE TASKS IN RATS.
The polyamines, spermine, spermidine and putrescine, are a group of aliphatic amines that interact with diverse cellular targets such as nucleic acids and proteins. The polyamines may act as physiological modulators of N-methyl-D-aspartate (NMDA) receptors. The processes mediated by NMDA receptor include synaptic plasticity and formation of neural circuitry.
Publicado em: 2004