Articular Incapacitation
Mostrando 1-7 de 7 artigos, teses e dissertações.
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1. Effect of strontium ranelate on pain behavior in an experimental model of osteoarthritis
Strontium ranelate (SrRan) is a drug usually prescribed to treat osteoporosis, with proven effects of decreasing the risk of fractures and an indication of reducing the progression of osteoarthritis (OA). This study aimed to investigate the effects of SrRan as either a prophylactic or a treatment drug, using an OA rat model to assess pain behavior. A monoiod
Braz J Med Biol Res. Publicado em: 07/08/2017
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2. Atividade física no tratamento de artrite induzida por adjuvante de Freund : efeitos na nocicepção, edema e migração celular / Physical activity in the treatment of CFA - induced arthritis : effect on nociception, edema and cell migration
O exercício físico apresenta potenciais benefícios na artrite, retardando a incapacidade funcional e melhorando a função das articulações. Sendo assim, o objetivo deste estudo foi avaliar a influência da atividade física sobre a nocicepção, edema e migração celular em ratas com artrite induzida por adjuvante completo de Freund (CFA), como també
Publicado em: 2008
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3. Estudo do efeito da fraÃÃo nÃo dialisÃvel do lÃtex de Calotropis procera (ait) R. Br em modelos experimentais de inflamaÃÃo, com Ãnfase em artrite / Study of the effect of the non-dialyzable fraction of Calotropis procera (Ait) R. Br latex in experimental models of inflammation, with emphasis in arthritis
The objective of this dissertation was to investigate the effect of the latex from Calotropis procera in experimental models of inflammation, with special focus on arthritis. The plant belongs to Asclepiadaceae family and is largely found in Northeast of Brazil. The plant latex presents clear anti-inflammatory effects, which is kept by its non-dialyzable pro
Publicado em: 2007
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4. Participação do óxido nítrico (NO) na modulação central da hiperalgesia na artrite induzida por zymozan (AZy) em ratos. / Nitric oxide (NO) participation in central hyperralgesia modulation in modulation in the zymozan induced artritis (AZy) in rats.
We investigate in this work the role of the central nervous system in the modulation of the inflammatory peripheral pain in the zymosan induced arthritis (AZy) in rats. Cerebrospinal fluid (CSF) and sinovial fluid were collected from animals at different AZy times (1, 3, 6, 12 and 14 hours) in order to determine the nitrite level. Different groups of male, W
Publicado em: 2006
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5. Potential effect of the antineoplasic Paclitaxel (Taxol) in the experimental inflammatory hyperalgisia induced by zymosan. / Efeito potencializador do antineoplásico paclitaxel (taxol) na hiperalgesia inflamatória experimental induzida por zymosan.
Paclitaxel (Taxol) was the first effective antineoplastic in the management of refractory neoplasias to the conventional chemotherapy. It induces clinically to myelosuppression and sensory peripheral neuropathy boundary and cumulative dose, well documented at literature already. Less often the patients exhibited myalgias and arthralgias. As to concern to the
Publicado em: 2003
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6. Study of the Antinociceptive activity of Thalidomide, Pentoxifillyne and Chlorpromazine in Experimental Models / Avaliação da atividade antinociceptiva da talidomida, pentoxifilina e clorpromazina em modelos experimentais.
The release of cyclo-oxygenase products and sympathomimetic amines, the final mediators of inflammatory pain, is preceded by the generation of pro-inflammatory and nociceptive cytokines by resident cells. Recently drugs such as thalidomide (TALD), pentoxifylline (PTX) and chlorpromazine (CLP), despite of other effects, have been associated with immunomodulat
Publicado em: 2003
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7. Atividade analgesica das interleucinas 4, 10 e 13 (IL-4, IL-10 e il-13) na dor inflamatoria experimental : papel de celulas residentes e citocinas / Analgesic activity of interleukines 4, 13 and 10 (IL-4, IL-13 and IL-10) in experimental inflammatory pain: role of resident cells and cytokines
The release of cyclo-oxigenase products and sympathomimetics amines, the final mediators of inflammatory pain, is preceded by the generation of cytokines by resident cells. In recent years a number of cytokines such as IL-4, IL-10, IL-13, IL-6, TGF-β e IFN-α have been described to inhibit the production of TNF-α, IL-1β, IL-6 and IL-8 (cyt
Publicado em: 2000