3D-GENOMICS: a database to compare structural and functional annotations of proteins between sequenced genomes
AUTOR(ES)
Fleming, Keiran
FONTE
Oxford University Press
RESUMO
The 3D-GENOMICS database (http://www.sbg.bio.ic.ac.uk/3dgenomics/) provides structural annotations for proteins from sequenced genomes. In August 2003 the database included data for 93 proteomes. The annotations stored in the database include homologous sequences from various sequence databases, domains from SCOP and Pfam, patterns from Prosite and other predicted sequence features such as transmembrane regions and coiled coils. In addition to annotations at the sequence level, several precomputed cross- proteome comparative analyses are available based on SCOP domain superfamily composition. Annotations are available to the user via a web interface to the database. Multiple points of entry are available so that a user is able to: (i) directly access annotations for a single protein sequence via keywords or accession codes, (ii) examine a sequence of interest chosen from a summary of annotations for a particular proteome, or (iii) access precomputed frequency-based cross-proteome comparative analyses.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=308798Documentos Relacionados
- Structural genomics and structural biology: compare and contrast
- The Genomic Threading Database: a comprehensive resource for structural annotations of the genomes from key organisms
- Gene3D: Structural Assignment for Whole Genes and Genomes Using the CATH Domain Structure Database
- Three Sequenced Legume Genomes and Many Crop Species: Rich Opportunities for Translational Genomics
- The CATH database: an extended protein family resource for structural and functional genomics
