A Decline in Mupirocin Resistance in Methicillin-Resistant Staphylococcus aureus Accompanied Administrative Control of Prescriptions
AUTOR(ES)
Walker, Elaine S.
FONTE
American Society for Microbiology
RESUMO
Susceptibility to mupirocin was assessed in methicillin-resistant Staphylococcus aureus isolates selected from eras corresponding to differences in usage rate and prescription policies at a Veterans Affairs medical center. The eras studied encompassed from the time of introduction of the drug to its widespread use, through recommended judicious use, and finally to subsequent stringent administrative control. Prescriptions declined from 3.0 to 0.1 per 1,000 patient days. Precipitous declines first in the numbers of isolates with high-level resistance (from 31% to 4%) and then in those with low-level resistance (from 26% to 10%) accompanied prescription control.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=427807Documentos Relacionados
- Efficacy of mupirocin in methicillin-resistant Staphylococcus aureus burn wound infection.
- Methicillin-resistant septal peptidoglycan synthesis in a methicillin-resistant Staphylococcus aureus strain.
- Methicillin-resistant Staphylococcus aureus.
- Low Concentrations of Mupirocin in the Pharynx following Intranasal Application May Contribute to Mupirocin Resistance in Methicillin-Resistant Staphylococcus aureus
- Transduction and Elimination of Resistance Determinants in Methicillin-Resistant Staphylococcus aureus