A drug-specific leuco-agglutinin in a fatal case of agranulocytosis due to chlorpromazine

AUTOR(ES)

Hoffman, G. C.

RESUMO

A fatal case of agranulocytosis due to chlorpromazine is reported. Mechanisms other than immunological are generally believed to be responsible for chlorpromazine-induced agranulocytosis. However, the demonstration of a drug-specific leuco-agglutinin in the serum of this patient suggests that an immunological mechanism was responsible for the agranulocytosis.

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