A dymanical approach to study the immunocompetence and the immunological tolerance of mammals.

AUTOR(ES)
FONTE

ANNUAL MEETING OF THE SOCITY FOR MATHEMATICAL BIOLOGY; INTERNATIONAL SYMPOSIUM ON MATHEMATICAL AND COMPUTATIONAL BIOLOGY

DATA DE PUBLICAÇÃO

2011

RESUMO

In this paper we present an in silico study about immune tolerance, where phase transitions have been observed when antigen dosages were varied in virtual samples. Using a dynamical model to study the behavior of the immune system - presented in a previous edition of the International Symposium on Mathematical and Computational Biology -, we have identified changes in the clonal memory capacity for minimum antigen concentration.

ASSUNTO(S)

imunocompetência tolerância imunológica de mamíferos estudo in silico modelo dinâmico dynamic models immunoassays

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