A FACTOR THAT STIMULATES RNA SYNTHESIS BY PURIFIED RNA POLYMERASE*

AUTOR(ES)
RESUMO

A protein factor, partially purified from E. coli, can stimulate some 30- to 50-fold the transcription of DNA by purified RNA polymerase. Evidence is presented suggesting that this stimulatory factor (designated M factor) exerts its effect before the RNA synthesis is initiated. The M factor is prepared from a crude ribosome fraction, but it does not require the presence of ribosomes for full activity.

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