A four-year surveillance program for detection of Plasmodium falciparum chloroquine resistance in Honduras
AUTOR(ES)
Fontecha, Gustavo A, Sanchez, Ana L, Mendoza, Meisy, Banegas, Engels, Mejía-Torres, Rosa E
FONTE
Mem. Inst. Oswaldo Cruz
DATA DE PUBLICAÇÃO
2014-07
RESUMO
Countries could use the monitoring of drug resistance in malaria parasites as an effective early warning system to develop the timely response mechanisms that are required to avert the further spread of malaria. Drug resistance surveillance is essential in areas where no drug resistance has been reported, especially if neighbouring countries have previously reported resistance. Here, we present the results of a four-year surveillance program based on the sequencing of the pfcrt gene of Plasmodium falciparum populations from endemic areas of Honduras. All isolates were susceptible to chloroquine, as revealed by the pfcrt “CVMNK” genotype in codons 72-76.
Documentos Relacionados
- Retinopathy of prematurity: review of a four-year period.
- Levobunolol compared with timolol: a four-year study.
- A four-year experience with splenectomy versus splenorrhaphy.
- A four-year experience with splenectomy versus splenorrhaphy.
- Epidemiology of Pseudomonas aeruginosa in a general hospital: a four-year study.