A Genetic Marker in the Variable Region of Light Chains of Mouse Immunoglobulins*
AUTOR(ES)
Edelman, Gerald M.
RESUMO
A genetic variation was observed upon autoradiographic comparison of tryptic peptide maps of 14C-labeled normal light chains from 17 different inbred strains of mice. The difference was found in strains AKR/J, C58/J, and RF/J. Chemical analyses showed that the differences were in a region of the amino acid sequence in the neighborhood of half-cystine I of the variable region of the light chain. Breeding experiments showed that the difference segregated in a classical Mendelian fashion.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=283336Documentos Relacionados
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