A longitudinal study of in vitro tests for lymphocyte function in rheumatoid arthritis

AUTOR(ES)
RESUMO

In vitro tests of lymphocyte function have been performed in 61 patients with `classical' or `definite' rheumatoid arthritis. In vitro lymphocyte function was assessed by lymphocyte transformation responses to phytohaemagglutinin (PHA), Pokeweed mitogen (PWM), Candida antigen, and herpes simplex type I (HSV1). Follow up data were available after 6 months of treatment in 32 of these patients. Spontaneous lymphocyte transformation was assessed in all patients. Results obtained in patients with rheumatoid arthiritis were compared to those seen in a normal control population. Disease activity of patients with rheumatoid arthritis was assessed using standard clinical methods.

Documentos Relacionados