A new non-linear normalization method for reducing variability in DNA microarray experiments
AUTOR(ES)
Workman, Christopher
FONTE
BioMed Central
RESUMO
A simple and robust non-linear method is presented for normalization using array signal distribution analysis and cubic splines. Both the regression and spline-based methods described performed better than existing linear methods when assessed on the variability of replicate arrays
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=126873Documentos Relacionados
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