A novel Arthrobacter beta-galactosidase with homology to eucaryotic beta-galactosidases.
AUTOR(ES)
Gutshall, K
RESUMO
An Arthrobacter beta-galactosidase has homology with the lysosomal acid beta-galactosidases from humans and mice and with a Xanthomonas manihotis enzyme. Phylogenetic analysis of the deduced amino acid sequence showed an unusual pattern, with this procaryotic enzyme clustering within the animal clade. The gene encodes a subunit of 52 kDa, and the enzyme appears to be active as a dimer. The enzyme hydrolyzed substrates with either a beta-1,4 or a beta-1,3 linkage.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=179077Documentos Relacionados
- Molecular basis of isozyme formation of beta-galactosidases in Bacillus stearothermophilus: isolation of two beta-galactosidase genes, bgaA and bgaB.
- Analysis of a novel gene and beta-galactosidase isozyme from a psychrotrophic Arthrobacter isolate.
- A polycistronic messenger RNA associated with beta-galactosidase induction.
- Vaccinia virus recombinants expressing an 11-kilodalton beta-galactosidase fusion protein incorporate active beta-galactosidase in virus particles.
- beta-Galactosidase chimeras: primary structure of a lac repressor-beta-galactosidase protein.
