A position effect on the expression of a tRNA gene mediated by the SIR genes in Saccharomyces cerevisiae.
AUTOR(ES)
Schnell, R
RESUMO
The SIR genes of Saccharomyces cerevisiae are responsible for the position-dependent regulation of the a and alpha mating-type genes. Previous work by others has shown that the products of the SIR genes prevent the accumulation of stable transcripts of the a and alpha genes at HML and HMR. Results of this study establish that this regulation is a region-specific effect rather than a gene-specific effect since expression of a tRNA gene placed at HMR is repressed by the products of the SIR genes.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=367538Documentos Relacionados
- Role of nuclear genes in expression of a mitochondrial tRNA gene in Saccharomyces cerevisiae.
- Transcripts of mitochondrial tRNA genes in Saccharomyces cerevisiae.
- Expression and function of a human initiator tRNA gene in the yeast Saccharomyces cerevisiae.
- Sequence and expression of four mutant aspartic acid tRNA genes from the mitochondria of Saccharomyces cerevisiae.
- Functional domains of SIR4, a gene required for position effect regulation in Saccharomyces cerevisiae.