A PROPOSED COMMON ALLOSTERIC MECHANISM FOR ACTIVE TRANSPORT, MUSCLE CONTRACTION, AND RIBOSOMAL TRANSLOCATION*
AUTOR(ES)
Hill, Terrell L.
RESUMO
It is suggested that active transport, muscle contraction, and ribosomal translocation may all make use of a common allosteric mechanism in which ATP or GTP serves as both the effector and substrate and in which a conformational change in a protein (enzyme) moves or exerts a force on a second ligand. The enzymatic splitting of ATP or GTP provides the driving force for the process and allows repetition of the steady-state cycle.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=286157Documentos Relacionados
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