A prospective study demonstrating the effect of 5% povidone-iodine application for anterior segment intraocular surgery in Paraguay
AUTOR(ES)
Quiroga, Lorena P., Lansingh, Van, Laspina, Florentina, Samudio, Margarita, Stanley, Jenny, Kaspar, Herminia Miño de, Cibils, Diógenes, Cibils, Pablo
FONTE
Arquivos Brasileiros de Oftalmologia
DATA DE PUBLICAÇÃO
2010-04
RESUMO
PURPOSE: To determine the conjunctival bacterial flora in cataract surgery patients and the effect of presurgical irrigation with 5% povidone-iodine solution. METHODS: Three samples from the inferior conjunctival fornix of the eye to be operated were obtained at baseline before washing (T0) with 10 ml 5% povidone-iodine solution, immediately after washing (T1), and upon completion of surgery (T2). Bacteria from the samples were inoculated in blood agar, chocolate agar, and thioglycolate broth. RESULTS: A total of 221 patients (n=224 eyes) with a mean age of 67 ± 13 years were included in the study. Bacteria from the (T0) samples were successfully grown in 73.2% of the thioglycolate agars, 21.0% of the blood agars, and 19.2% of the chocolate agars. Compared with T1 samples, the use of povidone-iodine wash translated into a 60.8% reduction (from 73.2% to 12.5%) in colonization of the conjunctiva (p<0.001), while no significant difference was found between the T1 and T2 samples. Conclusion: Conjunctival irrigation with a 5% povidone-iodine solution effectively reduces conjunctival flora and is therefore strongly recommended as a means of preventing postsurgical endophthalmitis following cataract surgery.
Documentos Relacionados
- Interaction of povidone-iodine compounds, phagocytic cells, and microorganisms.
- Increased bactericidal activity of dilute preparations of povidone-iodine solutions.
- Increased Bactericidal Activity of Dilute Preparations of Povidone-Iodine Solutions
- In Vitro Effectiveness of Povidone-Iodine on Acanthamoeba Isolates from Human Cornea
- Non-surgical instrumentation associated with povidone-iodine in the treatment of interproximal furcation involvements