A repetitive and apparently transposable DNA sequence in Dictyostelium discoideum associated with developmentally regulated RNAs.

AUTOR(ES)

Chung, S

RESUMO

Dictyostelium discoideum AX3 genomic DNA contains about 40 copies of a 4.5 Kb sequence. Each has the same restriction map, suggesting that they are all very similar. The sequences are scattered throughout the genome, and each of the six representative copies we cloned have different flanking sequences. Partial fragments of the 4.5 Kb sequence also are scattered throughout the genome. The DNA sequences flanking the 4.5 Kb repetitive sequences are different in different strains of Dictyostelium suggesting that the 4.5 Kb sequence is a transposable element. Each sub-region of this 4.5 Kb sequence is associated with a large number of mRNAs, all of which are developmentally regulated, but whose function is not known.

Documentos Relacionados

• Repetitive DNA sequences cotranscribed with developmentally regulated Dictyostelium discoideum mRNAs.
• A developmentally regulated cysteine proteinase in Dictyostelium discoideum.
• Nucleotide sequence of a late developmentally regulated prespore-enriched Dictyostelium discoideum gene.
• Dictyostelium discoideum mRNAs developmentally regulated during spore germination have short half-lives.
• Developmentally Regulated, Carbohydrate-Binding Protein in Dictyostelium discoideum