A search for retrovirus infection in systemic lupus erythematosus and rheumatoid arthritis.
AUTOR(ES)
Pelton, B K
RESUMO
Evidence for retroviral infection in general and human immunodeficiency virus (HIV) infection in particular was sought in freshly isolated peripheral blood T cells, B cells, and monocyte-macrophages from patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) and also in T cell and B cell lines established from the same source. Similar cells isolated from rheumatoid synovial membrane were also examined. The strategy used for the detection of virus was cocultivation with susceptible cell lines looking for syncytia formation, reverse transcriptase production, and nucleic acid hybridisation with HIV cDNA probes. No evidence for infection was obtained.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1003484Documentos Relacionados
- Proceedings: Systemic lupus erythematosus and rheumatoid arthritis.
- Respiratory function in systemic lupus erythematosus, scleroderma, and rheumatoid arthritis.
- Rheumatoid Arthritis and Systemic Lupus Erythematosus
- Continuation of long term treatment with hydroxychloroquine in systemic lupus erythematosus and rheumatoid arthritis.
- Altered immunoglobulin metabolism in systemic lupus erythematosus and rheumatoid arthritis