Abrogation of Ref1 Retrovirus Restriction in Human Cells
AUTOR(ES)
Towers, Greg
FONTE
American Society for Microbiology
RESUMO
We have previously described postentry restriction of murine leukemia virus in mammals. Here we characterize the block in human cells. Restricted infection kinetics are multiple hit at high virus dose, and restriction is abrogated by preexposure to restricted virus. We hypothesize that restricted capsid can titrate out the restriction factor.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=153820Documentos Relacionados
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