Acetyl CoA Carboxylase: The Purified Transcarboxylase Component

AUTOR(ES)
RESUMO

Acetyl CoA carboxylase of Escherichia coli has been resolved into three functionally dissimilar proteins: (1) biotin-carboxyl carrier protein (BCCP); (2) a biotin carboxylase component that catalyzes the Mn-ATP-dependent carboxylation of BCCP to form CO2--BCCP; and (3) a transcarboxylase component that catalyzes the transfer of the carboxyl group from CO2--BCCP to acetyl CoA to form malonyl CoA.

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