Actions of vasodilator nerves on arteriolar smooth muscle and neurotransmitter release from sympathetic nerves in the guinea-pig small intestine.
AUTOR(ES)
Kotecha, N
RESUMO
1. Brief constrictions of arterioles of the isolated submucosa of the guinea-pig small intestine were evoked by stimulation of the perivascular sympathetic nerves. Prior stimulation of vasodilator neurones in the submucosal nerve plexus greatly reduced the constrictor response to sympathetic stimulation. 2. Vasodilator nerve stimulation reduced both the amplitude and rate of decay of the excitatory junction potential (EJP) evoked in the arteriolar smooth muscle by sympathetic nerve stimulation. 3. Computer simulation of the effect of membrane resistance changes on the EJP amplitude indicated that the change in amplitude could not be explained by the fall in membrane resistance alone, suggesting that vasodilator nerve activity reduced neurotransmitter release from the sympathetic nerves.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1156853Documentos Relacionados
- Vasodilatation and smooth muscle membrane potential changes in arterioles from the guinea-pig small intestine.
- Effects of divalent cations on muscarinic receptor cationic current in smooth muscle from guinea-pig small intestine.
- Ca2+ inhibition of inositol trisphosphate-induced Ca2+ release in single smooth muscle cells of guinea-pig small intestine.
- Orally projecting interneurones in the guinea-pig small intestine.
- Substance P provoked gamma-aminobutyric acid release from the myenteric plexus of the guinea-pig small intestine.
