Activation of mouse peritoneal cells to kill Listeria monocytogenes by T-lymphocyte products.

AUTOR(ES)

Cole, P

RESUMO

An in vitro system has been used to demonstrate that glass-adherent mouse peritoneal cells can be activated to kill intracellular Listeria monocytogenes by antigen-stimulated T-lymphocytes derived from immunized mice. The soluble products of such stimulated lymphocyte cultures could only be shown to similarly activate peritoneal cells if the antigen used in both the immunization and lymphocyte stimulation was also present on the target intracellular organism.

Documentos Relacionados

• Accessory function of Kupffer cells in the antigen-specific blastogenic response of an L3T4+ T-lymphocyte clone to Listeria monocytogenes.
• Existing Antilisterial Immunity Does Not Inhibit the Development of a Listeria monocytogenes-Specific Primary Cytotoxic T-Lymphocyte Response
• T-lymphocyte clones responsive to Shigella flexneri.
• Cytotoxic T-lymphocyte antigen 4 blockade augments the T-cell response primed by attenuated Listeria monocytogenes resulting in more rapid clearance of virulent bacterial challenge
• Profound peripheral T-lymphocyte depletion and activation in disseminated tuberculosis