"Active" one-carbon generation in Saccharomyces cerevisiae.
AUTOR(ES)
Ogur, M
RESUMO
A new mutation introducing a one-carbon requirement (e.g., formate) for the glycine-supplemented growth of a serine-glycine auxotroph (ser1) was correlated with a lack of glycine decarboxylase activity. The presence of oxalate decarboxylase activity or glyoxylate decarboxylase activity did not overcome the one-carbon requirement. Another mutation characterized by the absence of oxalate decarboxylase activity did not introduce a one-carbon requirement. The presence and physiological significance of glycine decarboxylase activity in Saccharomyces are thus inferred.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=235031Documentos Relacionados
- One-Carbon Metabolism–Genome Interactions in Folate-Associated Pathologies12
- Regulation of One-Carbon Biosynthesis and Utilization in Escherichia coli
- One-carbon metabolism–related nutrients and prostate cancer survival123
- Genome-wide significant predictors of metabolites in the one-carbon metabolism pathway
- Enzymes involved in the assimilation of one-carbon units by Pseudomonas MS.