Activities of Isoniazid Alone and in Combination with Other Drugs against Mycobacterium avium Infection in Beige Mice
AUTOR(ES)
Fattorini, Lanfranco
FONTE
American Society for Microbiology
RESUMO
Monotherapy with isoniazid or amikacin or clarithromycin or combinations of two of these drugs showed nil to modest therapeutic activity in beige mice infected with Mycobacterium avium. However, the combination of all three, isoniazid-amikacin-clarithromycin, markedly reduced CFUs in both spleens and lungs after 91 days of infection.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=105526Documentos Relacionados
- Comparative activities of azithromycin and clarithromycin against Mycobacterium avium infection in beige mice.
- Activities of bay Y 3118, levofloxacin, and ofloxacin alone or in combination with ethambutol against Mycobacterium avium complex in vitro, in human macrophages, and in beige mice.
- Intracellular activities of roxithromycin used alone and in association with other drugs against Mycobacterium avium complex in human macrophages.
- Activities of Moxifloxacin Alone and in Combination with Other Antimicrobial Agents against Multidrug-Resistant Mycobacterium tuberculosis Infection in BALB/c Mice
- Activity of azithromycin against Mycobacterium avium infection in beige mice.