Activity of Selected Penicillins In Vitro and in Experimental Bacterial Infections in Mice

AUTOR(ES)
RESUMO

The minimal inhibitory concentration and the 50% mouse protective dose for five key penicillins are presented. Such data provide a useful guide in evaluating the activity of new penicillins, in comparison with those already commercially available, and establishes the amounts of antibiotic necessary to obtain a PD50 for several experimental model infections in mice.

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