Acute generalized exanthematous pustulosis induced by hydroxychloroquine: a case with atypical clinical presentation
AUTOR(ES)
Duman, Hatice, Topal, Ilteris Oguz, Kocaturk, Emek, Cure, Kubra, Mansuroglu, Ilknur
FONTE
An. Bras. Dermatol.
DATA DE PUBLICAÇÃO
2017-06
RESUMO
Abstract Acute generalized exanthematous pustulosis is a rare drug-induced eruption that is characterized by acute, nonfollicular sterile pustules on an erythematous and edematous base. The most frequently implicated drugs are beta-lactam antibiotics. Hydroxychloroquine has been widely used to treat dermatologic and rheumatologic diseases and has been reported as a rare cause of acute generalized exanthematous pustulosis. A 42-year-old female presented with pustular lesions on the skin surface with erythema, facial edema, and occasional atypical target-like lesions after 21 days of treatment with 200mg/day hydroxychloroquine for rheumatoid arthritis, diagnosed one month previously. We report a case with acute generalized exanthematous pustulosis induced by hydroxychloroquine and treated with dapsone and systemic corticosteroid.
Documentos Relacionados
- Acute generalized exanthematous pustulosis associated with spider bite
- T-cell involvement in drug-induced acute generalized exanthematous pustulosis
- Acute generalized exanthematous pustulosis with features mimicking toxic epidermal necrolysis secondary to amiodarone,
- Acute generalized exanthematous pustulosis x Von Zumbusch’s pustular psoriasis: A diagnostic challenge in a psoriatic patient
- Acute localized exanthematous pustulosis caused by cefoperazone and sodium sulbactam