Adenovirus type 5 virions can be assembled in vivo in the absence of detectable polypeptide IX.
AUTOR(ES)
Colby, W W
RESUMO
Mutant dl313 is an adenovirus type 5 deletion mutant which lacks 2,307 base pairs, including the 5' portion of the polypeptide IX gene. Mutant virions did not contain detectable levels of this polypeptide. They were substantially more thermolabile than wild-type particles and did not produce hexon nonomers upon pyridine disruption.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=171335Documentos Relacionados
- Adenovirus-Associated Virus Multiplication IX. Extent of Transcription of the Viral Genome In Vivo
- Constitutive episomal expression of polypeptide IX (pIX) in a 293-based cell line complements the deficiency of pIX mutant adenovirus type 5.
- Absence of Detectable Capping and Methylating Enzymes in Influenza Virions
- Polyamines in Type 5 Adenovirus-Infected Cells and Virions
- IX. Marginalidade
