Adult polycystic kidney disease and linked RFLPs at the alpha globin locus: a genetic study in the South Wales population.
AUTOR(ES)
Lazarou, L P
RESUMO
Thirteen South Wales kindreds with adult polycystic kidney disease have been studied for genetic linkage using the alpha globin and 3'HVR probes. A maximum lod score of 24.187 was found at a recombination fraction of 0.03. This study supports the existence of a single locus on chromosome 16 responsible for the disorder.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1050203Documentos Relacionados
- Estimating locus heterogeneity in autosomal dominant polycystic kidney disease (ADPKD) in the Spanish population.
- The orangutan adult alpha-globin gene locus: duplicated functional genes and a newly detected member of the primate alpha-globin gene family.
- Two BglII RFLPs of the human alpha-globin gene cluster in the American sickle cell population.
- New TaqI RFLPs at the DXS52 (St14) locus in the black population.
- New RFLPs at the DXS164 (pERT 87-8) locus in the black population.